Transcription Factor

						

			
Accessions: T154018_1.02 (CISBP 1.02), O04609 (JASPAR 2024), T18605 (AthalianaCistrome v4_May2016)

			
Names: T154018_1.02;, WRKY22, WRK22_ARATH, WRKY DNA-binding protein 22, WRKY transcription factor 22, AT4G01250, T18605;
Organisms: Arabidopsis thaliana
Libraries: CISBP 1.02 1, JASPAR 2024 2, AthalianaCistrome v4_May2016 3
1 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed]

2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]

3 O'Malley RC, Huang SS, Song L, Lewsey MG, Bartlett A, Nery JR, Galli M, Gallavotti A, Ecker JR. Cistrome and Epicistrome Features Shape the Regulatory DNA Landscape. Cell 165:1280-92 (2016). [Pubmed]
Notes: experiment type:PBM, family:WRKY, ecotype:Col-0, experiment type: ampDAP-seq, experiment type: ampDAP-seq (methyl-cytosines removed by PCR), experiment type: DAP-seq
Length: 298
Pfam Domains:   128-186 WRKY DNA -binding domain
Sequence: 
(in bold interface residues)		   1 MADDWDLHAVVRGCSAVSSSATTTVYSPGVSSHTNPIFTVGRQSNAVSFGEIRDLYTPFT   60
  61 QESVVSSFSCINYPEEPRKPQNQKRPLSLSASSGSVTSKPSGSNTSRSKRRKIQHKKVCH  120
 121 VAAEALNSDVWAWRKYGQKPIKGSPYPRGYYRCSTSKGCLARKQVERNRSDPKMFIVTYT  180
 181 AEHNHPAPTHRNSLAGSTRQKPSDQQTSKSPTTTIATYSSSPVTSADEFVLPVEDHLAVG  240
 241 DLDGEEDLLSLSDTVVSDDFFDGLEEFAAGDSFSGNSAPASFDLSWVVNSAATTTGGI
Interface Residues: 134, 135, 136, 138, 139, 150
3D-footprint Homologues: 6j4e_B, 6j4f_F, 6j4g_B, 6ir8_A, 7z0u_A
Binding Motifs: M1690_1.02 wwrgTcaamg
M0790 / MA1303.1 aAAAGTCAACkat
M0798 akmGTTGACTTTt
MA1303.2 AAAGTCAACk
Binding Sites: MA1303.1.16
MA1303.1.4
MA1303.1.5
MA1303.1.18
MA1303.1.20
MA1303.1.3
MA1303.1.1
MA1303.1.10
MA1303.1.11
MA1303.1.12
MA1303.1.13
MA1303.1.14
MA1303.1.15
MA1303.1.17
MA1303.1.19
MA1303.1.2
MA1303.1.6
MA1303.1.7
MA1303.1.8
MA1303.1.9
MA1303.2.3
MA1303.2.14
MA1303.2.7
MA1303.2.15
MA1303.2.1
MA1303.2.10
MA1303.2.11
MA1303.2.12
MA1303.2.13
MA1303.2.16
MA1303.2.17
MA1303.2.18
MA1303.2.19
MA1303.2.2
MA1303.2.20
MA1303.2.4
MA1303.2.5
MA1303.2.6
MA1303.2.8
MA1303.2.9
			
Publications:  Yu D, Chen C, Chen Z. 2001. Evidence for an important role of WRKY DNA binding proteins in the regulation of NPR1 gene expression. Plant Cell. 13:1527-40. [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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