Transcription Factor

Accessions: T153727_1.02 (CISBP 1.02), Q24040 (JASPAR 2024)
Names: Bgb, T153727_1.02;, BGB_DROME
Organisms: Drosophila melanogaster
Libraries: CISBP 1.02 1, JASPAR 2024 2
1 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed]
2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Uniprot: Q24040
Notes: experiment type:B1H
Length: 213
Pfam Domains: 30-195 Core binding factor beta subunit
Sequence:
(in bold interface residues)
1 MMNEAALANMIPYDTIGLYEQPKPRFIFKMPRVVPDQKSKFESDELFRRLSRESEVRYTG 60
61 YRERSIEERQVRFMNGCREGHTEASFVASGTNLQLVFNANQNPYLHDKECDFDKEHGKVH 120
121 IKSYFIMNGVCVRFRGWIDLERLDGVGCLEYDERRAMHEDAILRDQIDRYNQRLREFEDT 180
181 KRAYRDNRQDEMEAVRRGVASGGIGVGASMWRR
Interface Residues: 74, 101, 105, 126, 127, 130, 137, 152, 154
3D-footprint Homologues: 6ztj_C, 6vu3_A, 6vz3_A
Binding Motifs: MA0242.1 wAACCGCAR
M5173_1.02 YTGCGGTTw
Binding Sites: MA0242.1.1 / MA0242.1.16 / MA0242.1.17 / MA0242.1.18 / MA0242.1.2 / MA0242.1.3 / MA0242.1.4 / MA0242.1.5 / MA0242.1.6
MA0242.1.10 / MA0242.1.14 / MA0242.1.15 / MA0242.1.7 / MA0242.1.8
MA0242.1.11
MA0242.1.12
MA0242.1.13
MA0242.1.19
MA0242.1.20
MA0242.1.9
Publications: Meng X, Brodsky M.H, Wolfe S.A. A bacterial one-hybrid system for determining the DNA-binding specificity of transcription factors. Nature biotechnology 23:988-94 (2005). [Pubmed]
Related annotations: PaperBLAST

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