Transcription Factor

						

			
Accessions: P10243 (JASPAR 2024)

			
Names: A-Myb, Myb-like protein 1, Myb-related protein A, MYBA_HUMAN
Organisms: Homo sapiens
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Uniprot: P10243
Length: 752
Pfam Domains:     35-81 Myb-like DNA-binding domain
    38-98 Myb-like DNA-binding domain
   87-133 Myb-like DNA-binding domain
   90-147 Myb-like DNA-binding domain
  139-183 Myb-like DNA-binding domain
  142-195 Myb-like DNA-binding domain
  239-286 LMSTEN motif
  486-649 C-myb, C-terminal
Sequence: 
(in bold interface residues)		   1 MAKRSRSEDEDDDLQYADHDYEVPQQKGLKKLWNRVKWTRDEDDKLKKLVEQHGTDDWTL   60
  61 IASHLQNRSDFQCQHRWQKVLNPELIKGPWTKEEDQRVIELVQKYGPKRWSLIAKHLKGR  120
 121 IGKQCRERWHNHLNPEVKKSSWTEEEDRIIYEAHKRLGNRWAEIAKLLPGRTDNSIKNHW  180
 181 NSTMRRKVEQEGYLQDGIKSERSSSKLQHKPCAAMDHMQTQNQFYIPVQIPGYQYVSPEG  240
 241 NCIEHVQPTSAFIQQPFIDEDPDKEKKIKELEMLLMSAENEVRRKRIPSQPGSFSSWSGS  300
 301 FLMDDNMSNTLNSLDEHTSEFYSMDENQPVSAQQNSPTKFLAVEANAVLSSLQTIPEFAE  360
 361 TLELIESDPVAWSDVTSFDISDAAASPIKSTPVKLMRIQHNEGAMECQFNVSLVLEGKKN  420
 421 TCNGGNSEAVPLTSPNIAKFSTPPAILRKKRKMRVGHSPGSELRDGSLNDGGNMALKHTP  480
 481 LKTLPFSPSQFFNTCPGNEQLNIENPSFTSTPICGQKALITTPLHKETTPKDQKENVGFR  540
 541 TPTIRRSILGTTPRTPTPFKNALAAQEKKYGPLKIVSQPLAFLEEDIREVLKEETGTDLF  600
 601 LKEEDEPAYKSCKQENTASGKKVRKSLVLDNWEKEESGTQLLTEDISDMQSENRFTTSLL  660
 661 MIPLLEIHDNRCNLIPEKQDINSTNKTYTLTKKKPNPNTSKVVKLEKNLQSNCEWETVVY  720
 721 GKTEDQLIMTEQARRYLSTYTATSSTSRALIL
Interface Residues: 35, 70, 71, 74, 75, 78, 79, 80, 87, 121, 122, 123, 124, 126, 127, 130, 131, 132, 173, 174, 177, 178, 181, 182, 183
3D-footprint Homologues: 1w0t_A, 5eyb_B, 3osg_A, 7xur_A, 1vfc_A, 2kdz_A, 6kks_A, 1mse_C, 3zqc_A
Binding Motifs: MA0776.1 ACCGTTAACsgy
			
Publications: Tang H, Goldberg E. A-MYB (MYBL1) stimulates murine testis-specific Ldhc expression via the cAMP-responsive element (CRE) site. Biol Reprod 86:30 (2012). [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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