Transcription Factor
| Accessions: | O60682 (JASPAR 2024) |
| Names: | ABF-1, Activated B-cell factor 1, bHLHa22, Class A basic helix-loop-helix protein 22, MUSC_HUMAN, Musculin |
| Organisms: | Homo sapiens |
| Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Uniprot: | O60682 |
| Length: | 206 |
| Pfam Domains: | 108-160 Helix-loop-helix DNA-binding domain |
| Sequence: (in bold interface residues) | 1 MSTGSVSDPEEMELRGLQREYPVPASKRPPLRGVERSYASPSDNSSAEEEDPDGEEERCA 60 61 LGTAGSAEGCKRKRPRVAGGGGAGGSAGGGGKKPLPAKGSAAECKQSQRNAANARERARM 120 121 RVLSKAFSRLKTSLPWVPPDTKLSKLDTLRLASSYIAHLRQLLQEDRYENGYVHPVNLTW 180 181 PFVVSGRPDSDTKEVSAANRLCGTTA |
| Interface Residues: | 109, 112, 113, 115, 116, 117, 118, 119, 120 |
| 3D-footprint Homologues: | 7z5k_B, 2ypa_A, 6od3_F, 2ypa_B, 2ql2_A, 2ql2_D, 5nj8_C, 5v0l_B |
| Binding Motifs: | MA0665.1 AACAGCTGTT |
| Publications: | Macquarrie KL, Yao Z, Fong AP, Tapscott SJ. Genome-wide binding of the basic helix-loop-helix myogenic inhibitor musculin has substantial overlap with MyoD: implications for buffering activity. Skelet Muscle 3:26 (2013). [Pubmed] |
| Related annotations: | PaperBLAST |
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