Transcription Factor
| Accessions: | A4QPC8 (JASPAR 2024) |
| Names: | A4QPC8_MOUSE |
| Organisms: | Mus musculus |
| Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Uniprot: | A4QPC8 |
| Length: | 606 |
| Pfam Domains: | 11-35 C2H2-type zinc finger 67-87 Zinc finger, C2H2 type 67-87 C2H2-type zinc finger 67-87 C2H2-type zinc finger 79-103 Zinc-finger double domain 93-115 Zinc finger, C2H2 type 93-115 C2H2-type zinc finger 107-131 Zinc-finger double domain 121-144 Zinc finger, C2H2 type 121-144 C2H2-type zinc finger 121-144 C2H2-type zinc finger 135-161 Zinc-finger double domain 150-170 C2H2-type zinc finger 150-172 Zinc finger, C2H2 type 150-169 C2H2-type zinc finger 385-412 BED zinc finger 390-412 C2H2-type zinc finger 390-412 C2H2-type zinc finger 390-412 Zinc finger, C2H2 type 404-428 Zinc-finger double domain 418-433 C2H2-type zinc finger 418-441 C2H2-type zinc finger 418-441 Zinc finger, C2H2 type 432-457 Zinc-finger double domain 447-469 C2H2-type zinc finger 447-469 Zinc finger, C2H2 type |
| Sequence: (in bold interface residues) | 1 MAPDIHEERQHRCEDCDQLFESKAELADHQKFPCSTPHSAFSMVEEDLQQNLESESDLRE 60 61 IHGNQDCKECDRVFPDLQSLEKHMLSHTEEREYKCDQCPKAFNWKSNLIRHQMSHDSGKH 120 121 YECENCAKVFTDPSNLQRHIRSQHVGARAHACPECGKTFATSSGLKQHKHIHSSVKPFIS 180 181 FSQSMYPFPDRDLRSLPLKMEPQSPSEVKKLQKGSSESPFDLTTKRKDEKPLTSGPSKPS 240 241 GTPATSQDQPLDLSMGSRGRASGTKLTEPRKNHVFGEKKGSNMDTRPSSDGSLQHARPTP 300 301 FFMDPIYRVEKRKLTDPLEALKEKYLRPSPGFLFHPQMSAIENMAEKLESFSALKPEASE 360 361 LLQSVPSMFSFRAPPNTLPENLLRKGKERYTCRYCGKIFPRSANLTRHLRTHTGEQPYRC 420 421 KYCDRSFSISSNLQRHVRNIHNKEKPFKCHLCDRCFGQQTNLDRHLKKHENGNMSGTATS 480 481 SPHSELESAGAILDDKEDAYFTEIRNFIGNSNHGSQSPRNMEERMNGSHFKDKKALATSQ 540 541 NSDLLDDEEVEDEVLLDEEDEDNDIPGKPRKELGVTRLDEEIPEDDYEEAGALEMSCKAS 600 601 PVRHML |
| Interface Residues: | 22, 25, 28, 32, 45, 47, 50, 76, 77, 78, 79, 81, 82, 84, 85, 88, 103, 104, 105, 106, 107, 110, 131, 132, 133, 134, 135, 136, 137, 138, 139, 141, 160, 161, 162, 163, 164, 165, 166, 167, 168, 380, 390, 400, 401, 402, 403, 404, 407, 428, 429, 430, 431, 432, 434, 435, 439, 457, 458, 459, 460, 461, 462, 463, 464, 465, 468 |
| 3D-footprint Homologues: | 8ssu_A, 5kkq_D, 8ssq_A, 5yel_A, 5und_A, 1tf6_A, 6ml4_A, 5v3j_F, 8gn3_A, 5ei9_F, 7eyi_G, 7ysf_A, 2lt7_A, 2i13_A, 2jpa_A, 6jnm_A, 6a57_A, 7txc_E, 4m9v_C, 5yj3_D, 1ubd_C, 2kmk_A, 1tf3_A, 7w1m_H, 8cuc_F, 7y3l_A, 7n5w_A, 3uk3_C, 1f2i_J, 6wmi_A, 5k5i_A, 2gli_A, 1g2f_F, 4x9j_A, 1llm_D, 6blw_A, 6u9q_A, 1mey_C, 5kl3_A, 8h9h_G, 7y3m_I, 6e94_A, 2drp_D, 5k5l_F, 2wbs_A |
| Binding Motifs: | MA0029.1 aAGAyAAGATAAba MA0029.2 AGAyAAGATAA |
| Binding Sites: | MA0029.1.1 MA0029.1.10 MA0029.1.11 MA0029.1.12 MA0029.1.13 MA0029.1.14 MA0029.1.15 MA0029.1.16 MA0029.1.17 MA0029.1.18 MA0029.1.19 MA0029.1.2 MA0029.1.20 MA0029.1.3 MA0029.1.4 MA0029.1.5 MA0029.1.6 MA0029.1.7 MA0029.1.8 MA0029.1.9 |
| Publications: | Delwel R., Funabiki T., Kreider B. L., Morishita K., Ihle J. N. Four of the seven zinc fingers of the Evi-1 myeloid-transforming gene are required for sequence-specific binding to GA(C/T)AAGA(T/C)AAGATAA. Mol. Cell. Biol. 13:4291-4300 (1993). [Pubmed] |
| Related annotations: | PaperBLAST |
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.