Transcription Factor
| Accessions: | P28347 (JASPAR 2024) |
| Names: | NTEF-1, Protein GT-IIC, TCF-13, TEA domain family member 1, TEAD-1, TEAD1_HUMAN, Transcription factor 13, Transcriptional enhancer factor TEF-1 |
| Organisms: | Homo sapiens |
| Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Uniprot: | P28347 |
| Length: | 426 |
| Pfam Domains: | 9-418 TEA/ATTS domain family |
| Sequence: (in bold interface residues) | 1 MEPSSWSGSESPAENMERMSDSADKPIDNDAEGVWSPDIEQSFQEALAIYPPCGRRKIIL 60 61 SDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRKSRDFHSKLKDQTAKDKALQ 120 121 HMAAMSSAQIVSATAIHNKLGLPGIPRPTFPGAPGFWPGMIQTGQPGSSQDVKPFVQQAY 180 181 PIQPAVTAPIPGFEPASAPAPSVPAWQGRSIGTTKLRLVEFSAFLEQQRDPDSYNKHLFV 240 241 HIGHANHSYSDPLLESVDIRQIYDKFPEKKGGLKELFGKGPQNAFFLVKFWADLNCNIQD 300 301 DAGAFYGVTSQYESSENMTVTCSTKVCSFGKQVVEKVETEYARFENGRFVYRINRSPMCE 360 361 YMINFIHKLKHLPEKYMMNSVLENFTILLVVTNRDTQETLLCMACVFEVSNSEHGAQHHI 420 421 YRLVKD |
| Interface Residues: | 66, 70, 87, 88, 91, 92, 95, 96, 99, 200, 204 |
| 3D-footprint Homologues: | 5gzb_A, 5no6_N, 1oe4_B |
| Binding Motifs: | MA0090.1 yRCATTCCwsbg MA0090.2 yrCATTCCwy MA0090.3 hyACATTCCAGsm MA0090.4 ACATTCCAG |
| Binding Sites: | MA0090.3.1 MA0090.3.10 MA0090.3.11 / MA0090.3.7 MA0090.3.12 MA0090.3.13 MA0090.3.14 / MA0090.3.8 MA0090.3.15 / MA0090.3.9 MA0090.3.10 / MA0090.3.16 MA0090.3.17 MA0090.3.18 MA0090.3.11 / MA0090.3.19 MA0090.3.2 MA0090.3.20 MA0090.3.3 MA0090.3.3 / MA0090.3.4 MA0090.3.4 / MA0090.3.5 MA0090.3.6 MA0090.3.5 / MA0090.3.7 MA0090.3.8 MA0090.3.6 / MA0090.3.9 MA0090.3.12 MA0090.3.13 MA0090.3.14 MA0090.3.15 MA0090.3.16 MA0090.3.17 MA0090.3.18 MA0090.3.19 MA0090.3.20 MA0090.4.1 / MA0090.4.14 / MA0090.4.16 / MA0090.4.3 / MA0090.4.5 MA0090.4.10 MA0090.4.11 / MA0090.4.8 MA0090.4.12 / MA0090.4.17 MA0090.4.13 / MA0090.4.18 / MA0090.4.4 MA0090.4.15 MA0090.4.19 MA0090.4.2 MA0090.4.20 MA0090.4.6 MA0090.4.7 MA0090.4.9 |
| Publications: | Wasserman W.W, Fickett J.W. Identification of regulatory regions which confer muscle-specific gene expression. Journal of molecular biology 278:167-81 (1998). [Pubmed] Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed] |
| Related annotations: | PaperBLAST |
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