Transcription Factor

Accessions: P50207 (JASPAR 2024)
Names: HXC13_MOUSE
Organisms: Mus musculus
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Uniprot: P50207
Length: 328
Pfam Domains: 54-166 Hox protein A13 N terminal
259-315 Homeobox domain
Sequence:
(in bold interface residues)
1 MTTSLLLHPRWPESLMYVYEDSAAESGSGGGGGGGGAGGAGGGCSGASPGKAPSMDGLGG 60
61 SCPASHCRDLLPHPVLARPPAPLGAPQGAVYTDIPAPEAARQCAPPPAPPTSSSATLGYG 120
121 YPFGGSYYGCRLSHNVNLQQKPCAYHPGDKYPEPSGALPGDDLSSRAKEFAFYPSFASSY 180
181 QAMPGYLDVSVVPGISGHPEPRHDALIPVEGYQHWALSNGWDSQVYCSKEQSQSAHLWKS 240
241 PFPDVVPLQPEVSSYRRGRKKRVPYTKVQLKELEKEYAASKFITKEKRRRISATTNLSER 300
301 QVTIWFQNRRVKEKKVVSKSKAPHLHST
Interface Residues: 244, 258, 259, 260, 261, 262, 300, 301, 303, 304, 307, 308, 311, 312, 315
3D-footprint Homologues: 1e3o_C, 3a01_E, 5zfz_A, 1fjl_B, 3cmy_A, 2h1k_B, 6a8r_A, 1puf_A, 1ig7_A, 1jgg_B, 1nk2_P, 6m3d_C, 1zq3_P, 2lkx_A, 3lnq_A, 6es3_K, 2ld5_A, 7q3o_C, 4xrs_G, 1puf_B, 3rkq_B, 5flv_I, 5zjt_E, 4cyc_A, 7psx_B, 5hod_A, 1b72_A, 2r5y_A, 5jlw_D, 2hdd_A, 2xsd_C, 7xrc_C, 1au7_A, 1le8_A, 1mnm_C, 1du0_A, 1k61_B, 1o4x_A, 4qtr_D
Binding Motifs: PH0068.1 wwwkCTCrTAAAawtw
Publications: Berger M.F, Badis G, Gehrke A.R, Talukder S, Philippakis A.A, Peña-Castillo L, Alleyne T.M, Mnaimneh S, Botvinnik O.B, Chan E.T, Khalid F, Zhang W, Newburger D, Jaeger S.A, Morris Q.D, Bulyk M.L, Hughes T.R. Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences. Cell 133:1266-76 (2008). [Pubmed]
Related annotations: PaperBLAST

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.