Transcription Factor
| Accessions: | P50219 (JASPAR 2024) |
| Names: | Homeobox protein HB9, MNX1_HUMAN, Motor neuron and pancreas homeobox protein 1 |
| Organisms: | Homo sapiens |
| Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Uniprot: | P50219 |
| Length: | 401 |
| Pfam Domains: | 242-298 Homeobox domain |
| Sequence: (in bold interface residues) | 1 MEKSKNFRIDALLAVDPPRAASAQSAPLALVTSLAAAASGTGGGGGGGGASGGTSGSCSP 60 61 ASSEPPAAPADRLRAESPSPPRLLAAHCALLPKPGFLGAGGGGGGTGGGHGGPHHHAHPG 120 121 AAAAAAAAAAAAAAGGLALGLHPGGAQGGAGLPAQAALYGHPVYGYSAAAAAAALAGQHP 180 181 ALSYSYPQVQGAHPAHPADPIKLGAGTFQLDQWLRASTAGMILPKMPDFNSQAQSNLLGK 240 241 CRRPRTAFTSQQLLELEHQFKLNKYLSRPKRFEVATSLMLTETQVKIWFQNRRMKWKRSK 300 301 KAKEQAAQEAEKQKGGGGGAGKGGAEEPGAEELLGPPAPGDKGSGRRLRDLRDSDPEEDE 360 361 DEDDEDHFPYSNGASVHAASSDCSSEDDSPPPRPSHQPAPQ |
| Interface Residues: | 242, 243, 244, 245, 246, 283, 284, 286, 287, 290, 291, 294, 295, 298 |
| 3D-footprint Homologues: | 1fjl_B, 6a8r_A, 2h1k_B, 1puf_A, 1ig7_A, 3cmy_A, 5zfz_A, 3d1n_M, 5zjt_E, 3lnq_A, 2lkx_A, 1jgg_B, 6m3d_C, 1nk2_P, 1zq3_P, 2ld5_A, 7psx_B, 1au7_A, 5hod_A, 3a01_E, 7q3o_C, 1b72_A, 5jlw_D, 3rkq_B, 6es3_K, 4xrs_G, 2hdd_A, 4cyc_A, 2r5y_A, 1puf_B, 5flv_I, 2hos_A, 4j19_B, 1mnm_C, 1le8_A, 7xrc_C, 1e3o_C, 2xsd_C, 1k61_B, 1o4x_A, 4qtr_D, 1du0_A, 8g87_X |
| Binding Motifs: | MA0707.1 dsyAATTAaa MA0707.2 syrATTAk MA0707.3 yrATTA |
| Publications: | Noyes M.B, Christensen R.G, Wakabayashi A, Stormo G.D, Brodsky M.H, Wolfe S.A. Analysis of homeodomain specificities allows the family-wide prediction of preferred recognition sites. Cell 133:1277-89 (2008). [Pubmed] |
| Related annotations: | PaperBLAST |
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.