Transcription Factor
| Accessions: | P20615 (JASPAR 2024) |
| Names: | Homeobox protein Hox-2.5, Homeobox protein Hox-B9, HXB9_MOUSE |
| Organisms: | Mus musculus |
| Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Uniprot: | P20615 |
| Length: | 250 |
| Pfam Domains: | 1-172 Hox9 activation region 186-242 Homeobox domain |
| Sequence: (in bold interface residues) | 1 MSISGTLSSYYVDSIISHESEDAPPAKFPSGQYANPRQPGHAEHLDFPSCSFQPKAPVFG 60 61 ASWAPLSPHASGSLPSVYHPYLQPQGAPAAESRYLRTWLEPAPRAEAAPGQGQAAVKAEP 120 121 LLGAPGELLKQGTPEYSLETSAGREAVLSNQRAGYGDNKICEGSEDKERPDQTNPSANWL 180 181 HARSSRKKRCPYTKYQTLELEKEFLFNMYLTRDRRHEVARLLNLSERQVKIWFQNRRMKM 240 241 KKMNKEQGKE |
| Interface Residues: | 186, 187, 188, 189, 227, 228, 230, 231, 234, 235, 238, 239, 240, 242 |
| 3D-footprint Homologues: | 1puf_A, 1ig7_A, 3cmy_A, 3d1n_M, 6a8r_A, 1fjl_B, 2h1k_B, 5zfz_A, 2lkx_A, 1nk2_P, 1zq3_P, 7q3o_C, 2ld5_A, 6es3_K, 6m3d_C, 5flv_I, 2hdd_A, 5zjt_E, 4cyc_A, 2r5y_A, 1puf_B, 1jgg_B, 7psx_B, 2hos_A, 5jlw_D, 3lnq_A, 4xrs_G, 3a01_E, 1b72_A, 3rkq_B, 1e3o_C, 2xsd_C, 1au7_A, 1le8_A, 7xrc_C, 1mnm_C, 8g87_X, 1du0_A, 5hod_A, 4qtr_D, 1k61_B, 1o4x_A |
| Binding Motifs: | PH0064.1 rrrgymATWAAAwycr |
| Publications: | Berger M.F, Badis G, Gehrke A.R, Talukder S, Philippakis A.A, Peña-Castillo L, Alleyne T.M, Mnaimneh S, Botvinnik O.B, Chan E.T, Khalid F, Zhang W, Newburger D, Jaeger S.A, Morris Q.D, Bulyk M.L, Hughes T.R. Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences. Cell 133:1266-76 (2008). [Pubmed] |
| Related annotations: | PaperBLAST |
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