Transcription Factor
Accessions: | Abd-B (DrosophilaTF 1.1), P09087 (JASPAR 2024) |
Names: | ABDB_DROME, Homeobox protein abdominal-B, IAB-7, Infraabdominal 7, P3, PH189 |
Organisms: | Drosophila melanogaster |
Libraries: | DrosophilaTF 1.1 1, JASPAR 2024 2 1 Down T.A, Bergman C.M, Su J, Hubbard T.J. Large-scale discovery of promoter motifs in Drosophila melanogaster. PLoS computational biology 3:e7 (2007). [Pubmed] 2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
Uniprot: | P09087 |
Length: | 493 |
Pfam Domains: | 388-444 Homeobox domain |
Sequence: (in bold interface residues) | 1 MQQHHLQQQQQQQQQQEQQHLQEQQQHLQQLHHHAHHHLPQPLHTTSHHHSAHPHLQQQQ 60 61 QQQQHAVVASSPSSVLQQQQQQSTPTTHSTPTHAVMYEDPPPVPLVAVQQQHLPAPQQQQ 120 121 QLQQQQQQQQQQLATTPVAGALSPAQTPTGPSAQQQQHLTSPHHQQLPQQQTPNSVASGA 180 181 SSNLQQQQQQQNAAVAPGQTQIVAPTTASVSPSSVSSQKEDINMSIQLAPLHIPAIRAGP 240 241 GFETDTSAAVKRHTAHWAYNDEGFNQHYGSGYYDRKHMFAYPYPETQFPVGQYWGPNYRP 300 301 DQTTSAAAAAAYMNEAERHVSAAARQSVEGTSTSSYEPPTYSSPGGLRGYPSENYSSSGA 360 361 SGGLSVGAVGPCTPNPGLHEWTGQVSVRKKRKPYSKFQTLELEKEFLFNAYVSKQKRWEL 420 421 ARNLQLTERQVKIWFQNRRMKNKKNSQRQANQQNNNNNSSSNHNHAQATQQHHSGHHLNL 480 481 SLNMGHHAAKMHQ |
Interface Residues: | 388, 389, 390, 391, 394, 429, 430, 432, 433, 436, 437, 440, 441, 444 |
3D-footprint Homologues: | 1puf_A, 3cmy_A, 5zfz_A, 1fjl_B, 1ig7_A, 6a8r_A, 2h1k_B, 3lnq_A, 2lkx_A, 1jgg_B, 6m3d_C, 1nk2_P, 1zq3_P, 6es3_K, 2ld5_A, 7q3o_C, 4xrs_G, 2hdd_A, 3rkq_B, 2r5y_A, 1puf_B, 1au7_A, 5flv_I, 3d1n_M, 2hos_A, 5zjt_E, 4cyc_A, 7psx_B, 1b72_A, 3l1p_A, 3a01_E, 5jlw_D, 7xrc_C, 1e3o_C, 2xsd_C, 1le8_A, 1mnm_C, 1k61_B, 8g87_X, 5hod_A, 1o4x_A, 4qtr_D, 1le8_B, 1du0_A |
Binding Motifs: | MA0165.1 TTTATka Abd-B rsvTTtATGgCsvs |
Binding Sites: | MA0165.1.1 MA0165.1.10 MA0165.1.11 MA0165.1.12 MA0165.1.13 MA0165.1.14 MA0165.1.15 MA0165.1.16 MA0165.1.17 MA0165.1.18 / MA0165.1.19 MA0165.1.2 MA0165.1.20 MA0165.1.3 MA0165.1.4 MA0165.1.5 MA0165.1.6 MA0165.1.7 MA0165.1.8 MA0165.1.9 |
Publications: | Ekker S. C., Jackson D. G., von Kessler D. P., Sun B. I., Young K. E., Beachy P. A. The degree of variation in DNA sequence recognition among four Drosophila homeotic proteins. EMBO J. 13:3551-3560 (1994). [Pubmed] Noyes M.B, Meng X, Wakabayashi A, Sinha S, Brodsky M.H, Wolfe S.A. A systematic characterization of factors that regulate Drosophila segmentation via a bacterial one-hybrid system. Nucleic acids research 36:2547-60 (2008). [Pubmed] |
Related annotations: | PaperBLAST |
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