Transcription Factor
| Accessions: | Q8N693 (JASPAR 2024) |
| Names: | ESX1_HUMAN, Extraembryonic, spermatogenesis, homeobox 1, Homeobox protein ESX1 |
| Organisms: | Homo sapiens |
| Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Length: | 406 |
| Pfam Domains: | 140-196 Homeobox domain |
| Sequence: (in bold interface residues) | 1 MESLRGYTHSDIGYRSLAVGEDIEEVNDEKLTVTSLMARGGEDEENTRSKPEYGTEAENN 60 61 VGTEGSVPSDDQDREGGGGHEPEQQQEEPPLTKPEQQQEEPPLLELKQEQEEPPQTTVEG 120 121 PQPAEGPQTAEGPQPPERKRRRRTAFTQFQLQELENFFDESQYPDVVARERLAARLNLTE 180 181 DRVQVWFQNRRAKWKRNQRVLMLRNTATADLAHPLDMFLGGAYYAAPALDPALCVHLVPQ 240 241 LPRPPVLPVPPMPPRPPMVPMPPRPPIAPMPPMAPVPPGSRMAPVPPGPRMAPVPPWPPM 300 301 APVPPWPPMAPVPTGPPMAPVPPGPPMARVPPGPPMARVPPGPPMAPLPPGPPMAPLPPG 360 361 PPMAPLPPGPPMAPLPPRSHVPHTGLAPVHITWAPVINSYYACPFF |
| Interface Residues: | 140, 141, 142, 143, 145, 181, 182, 184, 185, 188, 189, 192, 193, 196 |
| 3D-footprint Homologues: | 5zfz_A, 1ig7_A, 2h1k_B, 1puf_A, 6a8r_A, 3cmy_A, 1fjl_B, 3d1n_M, 1nk2_P, 1zq3_P, 6m3d_C, 4j19_B, 1jgg_B, 3lnq_A, 2lkx_A, 2ld5_A, 7q3o_C, 6es3_K, 2hos_A, 1b72_A, 4cyc_A, 5flv_I, 3l1p_A, 5zjt_E, 3a01_E, 7psx_B, 5hod_A, 2hdd_A, 1au7_A, 5jlw_D, 3rkq_B, 2r5y_A, 1puf_B, 4xrs_G, 7xrc_C, 2xsd_C, 1e3o_C, 1le8_A, 1o4x_A, 8g87_X, 1du0_A, 4qtr_D |
| Binding Motifs: | MA0644.1 rcyAATTArc MA0644.2 yyAATTAv MA0644.3 yyAATTA |
| Publications: | Berger M.F, Badis G, Gehrke A.R, Talukder S, Philippakis A.A, Peña-Castillo L, Alleyne T.M, Mnaimneh S, Botvinnik O.B, Chan E.T, Khalid F, Zhang W, Newburger D, Jaeger S.A, Morris Q.D, Bulyk M.L, Hughes T.R. Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences. Cell 133:1266-76 (2008). [Pubmed] |
| Related annotations: | PaperBLAST |
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.