Transcription Factor
Accessions: | T061552_1.02 (CISBP 1.02), P33749 (JASPAR 2024) |
Names: | MSN4, T061552_1.02;, MSN4_YEAST, Multicopy suppressor of SNF1 protein 4, Zinc finger protein MSN4 |
Organisms: | Saccharomyces cerevisiae |
Libraries: | CISBP 1.02 1, JASPAR 2024 2 1 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed] 2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
Notes: | experiment type:PBM, family:C2H2 ZF |
Length: | 630 |
Pfam Domains: | 573-596 C2H2-type zinc finger 573-596 Zinc finger, C2H2 type 587-613 Zinc-finger double domain 602-624 Zinc finger, C2H2 type 602-624 C2H2-type zinc finger |
Sequence: (in bold interface residues) | 1 MLVFGPNSSFVRHANKKQEDSSIMNEPNGLMDPVLSTTNVSATSSNDNSANNSISSPEYT 60 61 FGQFSMDSPHRTDATNTPILTATTNTTANNSLMNLKDTASLATNWKWKNSNNAQFVNDGE 120 121 KQSSNANGKKNGGDKIYSSVATPQALNDELKNLEQLEKVFSPMNPINDSHFNENIELSPH 180 181 QHATSPKTNLLEAEPSIYSNLFLDARLPNNANSTTGLNDNDYNLDDTNNDNTNSMQSILE 240 241 DFVSSEEALKFMPDAGRDARRYSEVVTSSFPSMTDSRNSISHSIEFWNLNHKNSSNSKPT 300 301 QQIIPEGTATTERRGSTISPTTTINNSNPNFKLLDHDVSQALSGYSMDFSKDSGITKPKS 360 361 ISSSLNRISHSSSTTRQQRASLPLIHDIESFANDSVMANPLSDSASFLSEENEDDAFGAL 420 421 NYNSLDATTMSAFDNNVDPFNILKSSPAQDQQFIKPSMMLSDNASAAAKLATSGVDNITP 480 481 TPAFQRRSYDISMNSSFKILPTSQAHHAAQHHQQQPTKQATVSPNTRRRKSSSVTLSPTI 540 541 SHNNNNGKVPVQPRKRKSITTIDPNNYDKNKPFKCKDCEKAFRRSEHLKRHIRSVHSTER 600 601 PFACMFCEKKFSRSDNLSQHLKTHKKHGDF |
Interface Residues: | 406, 556, 558, 573, 583, 584, 585, 586, 587, 589, 590, 591, 612, 613, 614, 615, 616, 617, 618, 619, 620, 623 |
3D-footprint Homologues: | 8gh6_A, 2gli_A, 2kmk_A, 1g2f_F, 5v3j_F, 8cuc_F, 7y3l_A, 3uk3_C, 7n5w_A, 8ssu_A, 6u9q_A, 5und_A, 8gn3_A, 6blw_A, 5k5l_F, 2lt7_A, 7ysf_A, 6wmi_A, 4x9j_A, 2i13_A, 1llm_D, 7w1m_H, 5kkq_D, 2wbs_A, 1ubd_C, 5yel_A, 5ei9_F, 2jpa_A, 8ssq_A, 1mey_C, 6ml4_A, 5kl3_A, 2drp_D, 1f2i_J, 5k5i_A, 4m9v_C, 8h9h_G, 1tf3_A, 7y3m_I, 1tf6_A, 6e94_A, 7eyi_G, 7txc_E, 5yj3_D |
Binding Motifs: | M0527_1.02 yarGGGGy MA0342.1 AGGGG |
Publications: | Badis G, Chan E.T, van Bakel H, Pena-Castillo L, Tillo D, Tsui K, Carlson C.D, Gossett A.J, Hasinoff M.J, Warren C.L, Gebbia M, Talukder S, Yang A, Mnaimneh S, Terterov D, Coburn D, Li Yeo A, Yeo Z.X, Clarke N.D, Lieb J.D, Ansari A.Z, Nislow C, Hughes T.R. A library of yeast transcription factor motifs reveals a widespread function for Rsc3 in targeting nucleosome exclusion at promoters. Molecular cell 32:878-87 (2008). [Pubmed] |
Related annotations: | PaperBLAST |
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