Transcription Factor

Accessions: T100212_1.02 (CISBP 1.02), Q04116 (JASPAR 2024)
Names: T100212_1.02;, YHP1, YHP1_YEAST
Organisms: Saccharomyces cerevisiae
Libraries: CISBP 1.02 1, JASPAR 2024 2
1 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed]
2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: experiment type:PBM, family:Homeodomain
Length: 353
Pfam Domains: 174-230 Homeobox domain
Sequence:
(in bold interface residues)
1 MESRNTVLPSLPNIITGTSNSPFQLHTLPNTNFPSDDQGDIRLPPLAASAHIVRPVVNIY 60
61 KSPCDEERPKRKSPQAVDFLSQRVTTSMTPLSKPKKLSSHSPFTPTVRVCSKEQPPQSMH 120
121 SYKKVNILTPLSAAKAVLTPTTRKEKKRSFAFITHSQETFPKKEPKIDNARLARRKRRRT 180
181 SSYELGILQTAFDECPTPNKAKRIELSEQCNMSEKSVQIWFQNKRQAAKKHKNSGNTSHC 240
241 KVHSNDSMSMISYSDAALEITSTPTSTKEAITAELLKTSPANTSSIFEDHHITPCKPGGQ 300
301 LKFHRKSVLVKRTLSNTGHSEIIKSPKGKENRLKFNAYERKPLGEVDLNSFKN
Interface Residues: 174, 175, 176, 177, 178, 179, 180, 215, 216, 218, 219, 222, 223, 226, 227, 229, 230
3D-footprint Homologues: 2h1k_B, 6a8r_A, 3cmy_A, 1fjl_B, 5zfz_A, 4j19_B, 1jgg_B, 3lnq_A, 2lkx_A, 1zq3_P, 1nk2_P, 2ld5_A, 5hod_A, 5jlw_D, 3rkq_B, 1puf_B, 4xrs_G, 3d1n_M, 1b72_A, 4cyc_A, 5zjt_E, 1au7_A, 3l1p_A, 1e3o_C, 1le8_A, 7q3o_C, 7xrc_C, 2xsd_C, 1ig7_A, 7psx_B, 1puf_A, 4qtr_D, 2hdd_A, 2r5y_A, 6es3_K, 6m3d_C, 5flv_I, 1o4x_A, 8g87_X, 1du0_A, 3a01_E, 2hos_A
Binding Motifs: M1135_1.02 ayyaATwwa
MA0426.1 TAATTG
Publications: MacIsaac K.D, Wang T, Gordon D.B, Gifford D.K, Stormo G.D, Fraenkel E. An improved map of conserved regulatory sites for Saccharomyces cerevisiae. BMC bioinformatics 7:113 (2006). [Pubmed]
Related annotations: PaperBLAST

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