Transcription Factor

Accessions: T107917_1.02 (CISBP 1.02)
Names: AAH82862, T107917_1.02;
Organisms: Xenopus laevis
Libraries: CISBP 1.02 1
1 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed]
Notes: experiment type:PBM, family:IRF
Length: 517
Pfam Domains: 7-115 Interferon regulatory factor transcription factor
267-448 Interferon-regulatory factor 3
Sequence:
(in bold interface residues)
1 MNSHHRRVRLKPWLVAQVDSGQYPGLHWEDQDRKVFRIPWRHATRHIPIQEDENTVFKAW 60
61 AKETGKYQEGVDEPDPAKWKANLRCALNKSREFNLLYDGTKETPVQPFKIYQLCDLPGQN 120
121 EEPIGGDDIGGDDEEEIGARFPMLHISDSLCPPVQDSLPPFIWPKAEPNFPSSCSNHNFP 180
181 GPRDIVQHNRTAQTTAITPVPTGAYSEVDMSPQSLVSQSTVLPLPELVPGSGLEPSSDVE 240
241 LSVQGGIPPIHQGIPDLLISPQMLPLTDLEIKFLYRGKQAGAMTVSNPHGCRLFYSNLEP 300
301 TPEQVELFGPTSLEQVRFPGTEGIGNEKQKFYTNHLLDVMDRGLILCLQGQDIYAIRLCQ 360
361 CKVFWSGPCAGYTDRPNPIEREKRIKLFSLETFLNELIACQKGHTSSLPPYEIFFCFGEE 420
421 WPDRKPKEKKLITVQVIPVAARLLSEIFTGESSWSADSIRLQISHPDLKDKMVEQFKELH 480
481 QLWQSQQAPAVAQVEAIPNPECDVGSGPWPMHTGNME
Interface Residues: 42, 44, 77, 81, 82, 84, 85, 88, 89
3D-footprint Homologues: 2pi0_B, 1if1_B, 2o61_A, 2irf_L, 7oot_B
Binding Motifs: M1273_1.02 rccGAaACyr
Related annotations: PaperBLAST

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.