Transcription Factor
| Accessions: | T120868_1.02 (CISBP 1.02), Q02457 (JASPAR 2024) |
| Names: | T120868_1.02;, TBF1, Protein TBF1, TBF-alpha, TBF1_YEAST, TTAGGG repeat-binding factor 1 |
| Organisms: | Saccharomyces cerevisiae |
| Libraries: | CISBP 1.02 1, JASPAR 2024 2 1 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed] 2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Notes: | experiment type:PBM, family:Myb/SANT |
| Length: | 562 |
| Pfam Domains: | 30-303 Telomere repeat binding factor (TRF) 410-464 Myb-like DNA-binding domain |
| Sequence: (in bold interface residues) | 1 MDSQVPNNNESLNRFNDIIQSLPARTRLTICSLCLLDNISTQLLRFLILNANSPNIIAVL 60 61 TDQTAFLSSGETEIFQTLVKLFKQIRMIYHTRSPLLSVHDVAPGLWFPNSPPPLILRGHE 120 121 AFIITAIRKANLLTFLLTSLNCLNYGFELLQSIFLDIFCPNTNTVGNNSLEQSGKFLKSQ 180 181 AILYLDLKTQAYIAGLKEFQDETNEISLEKKQELLDLIFPSNLADILVQRRTGDSGDITL 240 241 LTPSEKDFVERCDRRRENLKIVQDFNSLTQSYEWAQFIRELLDYCNKNMGLIIWGRKGRG 300 301 KSPLYDFDVNEFDPQVLFSTGTRTVEFMDDQNQPSSASAFLSTARPNHYSTHTPTTDVSS 360 361 KNPAITQSIVDAAVAASMSNSSSGPHSSHNNSSNSNNNGSIGLRKPKAKRTWSKEEEEAL 420 421 VEGLKEVGPSWSKILDLYGPGGKITENLKNRTQVQLKDKARNWKLQYLKSGKPLPDYLIK 480 481 VTGNLEKIYKAKKKFSQSPNSSTIMEQNLSQHPSSAASATEDTQTHQEDSHGQNSDNMPS 540 541 NGLFGNSTSDNTGFDPHLEDGM |
| Interface Residues: | 409, 445, 446, 449, 450, 451, 452, 453, 454, 455, 457, 458, 461 |
| 3D-footprint Homologues: | 7c4r_A, 1w0t_A, 1mse_C, 2kdz_A, 3osg_A |
| Binding Motifs: | M1376_1.02 ArCCCTAr MA0403.1 arCCCTAr MA0403.2 wwhwAACCCTAAmwww MA0403.3 AACCCTAA |
| Binding Sites: | MA0403.3.12 / MA0403.3.3 / MA0403.3.5 / MA0403.3.6 / MA0403.3.7 MA0403.3.14 / MA0403.3.18 / MA0403.3.19 / MA0403.3.4 MA0403.3.13 MA0403.3.10 / MA0403.3.2 / MA0403.3.8 / MA0403.3.9 MA0403.3.1 / MA0403.3.15 / MA0403.3.20 MA0403.3.16 MA0403.2.1 MA0403.2.10 / MA0403.2.15 MA0403.2.11 / MA0403.2.17 MA0403.2.12 / MA0403.2.18 MA0403.2.13 / MA0403.2.19 MA0403.2.14 / MA0403.2.18 / MA0403.2.20 MA0403.2.15 MA0403.2.16 MA0403.2.17 MA0403.2.19 MA0403.2.2 MA0403.2.20 MA0403.2.3 MA0403.2.4 / MA0403.2.6 MA0403.2.5 / MA0403.2.8 MA0403.2.10 / MA0403.2.6 MA0403.2.11 / MA0403.2.7 MA0403.2.12 / MA0403.2.13 / MA0403.2.8 / MA0403.2.9 MA0403.2.14 MA0403.2.16 MA0403.2.4 MA0403.2.5 MA0403.2.7 MA0403.2.9 MA0403.3.11 MA0403.3.17 |
| Publications: | Badis G, Chan E.T, van Bakel H, Pena-Castillo L, Tillo D, Tsui K, Carlson C.D, Gossett A.J, Hasinoff M.J, Warren C.L, Gebbia M, Talukder S, Yang A, Mnaimneh S, Terterov D, Coburn D, Li Yeo A, Yeo Z.X, Clarke N.D, Lieb J.D, Ansari A.Z, Nislow C, Hughes T.R. A library of yeast transcription factor motifs reveals a widespread function for Rsc3 in targeting nucleosome exclusion at promoters. Molecular cell 32:878-87 (2008). [Pubmed] |
| Related annotations: | PaperBLAST |
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