Transcription Factor
| Accessions: | T049124_1.02 (CISBP 1.02), Q64321 (JASPAR 2024) |
| Names: | T049124_1.02;, Zbtb7b, c-Krox, Krueppel-related zinc finger protein cKrox, T-helper-inducing POZ/Krueppel-like factor, ZBT7B_MOUSE, Zfp-67, Zinc finger and BTB domain-containing protein 7B, Zinc finger protein 67, Zinc finger protein Th-POK |
| Organisms: | Mus musculus |
| Libraries: | CISBP 1.02 1, JASPAR 2024 2 1 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed] 2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Notes: | experiment type:PBM, family:C2H2 ZF |
| Length: | 544 |
| Pfam Domains: | 24-144 BTB/POZ domain 367-389 Zinc-finger double domain 378-400 C2H2-type zinc finger 378-400 Zinc finger, C2H2 type 393-417 Zinc-finger double domain 406-428 C2H2-type zinc finger 420-444 Zinc-finger double domain 434-454 C2H2-type zinc finger 434-454 Zinc finger, C2H2 type |
| Sequence: (in bold interface residues) | 1 MGSPEDDLIGIPFPDHSSELLSCLNEQRQLGHLCDLTIRTQGLEYRTHRAVLAACSHYFK 60 61 KLFTEGGGGTVMGTGGGGTASGGAGAGVCELDFVGPEALGALLEFAYTATLTTSSANMPA 120 121 VLQAARLLEIPCVIAACMEILQGSGLEAPSPDEDDCERARQYLEAFATATTTASTSGMPN 180 181 GEDSPPQVPLLPPPPPPPRPVARRSRKPRKAFLQTKGARANHLVPEAPTVLTHPLTYEEE 240 241 EMVGRLGNSGGSGLGDSYSPPTGAASPAEGPLNYEVFEGEEEEEEMAYPPGYGLAQSNEP 300 301 SLSPEELGSDEDPIDPDLMAYLSSLHQDALTPGLDGQDKLVRKRRSQMPQECPVCHKIIH 360 361 GAGKLPRHMRTHTGEKPFACEVCGVRFTRNDKLKIHMRKHTGERPYSCPHCPARFLHSYD 420 421 LKNHMHLHTGDRPYECHLCHKAFAKEDHLQRHLKGQNCLEVRTRRRRKDDVAAPHYPPPS 480 481 TTTSSPAGLDLSNGHLDTFHLSLARFWEQSATTGPPVTTQGPPEEEEEEGTPTTPQAEGA 540 541 MESS |
| Interface Residues: | 338, 339, 343, 346, 347, 360, 361, 362, 363, 364, 366, 367, 369, 370, 373, 378, 388, 389, 390, 391, 392, 394, 395, 396, 399, 416, 417, 418, 419, 420, 421, 422, 423, 424, 427, 444, 445, 446, 447, 448, 450, 451, 485, 486, 489, 492 |
| 3D-footprint Homologues: | 2i13_A, 1yuj_A, 8cuc_F, 7y3l_A, 7n5w_A, 3uk3_C, 5k5i_A, 8ssq_A, 7w1m_H, 5und_A, 1llm_D, 8ssu_A, 6ml4_A, 5v3j_F, 4x9j_A, 6blw_A, 5kkq_D, 5ei9_F, 7eyi_G, 8h9h_G, 7y3m_I, 6e94_A, 7ysf_A, 6wmi_A, 1tf6_A, 2jpa_A, 1ubd_C, 2kmk_A, 6jnm_A, 1tf3_A, 2gli_A, 5k5l_F, 1mey_C, 6u9q_A, 5yel_A, 7txc_E, 5kl3_A, 1g2f_F, 4m9v_C, 2lt7_A, 6a57_A, 8gn3_A, 2wbs_A, 1f2i_J, 2drp_D, 5yj3_D |
| Binding Motifs: | PB0092.1 rrgCCCCCCwaawat PB0196.1 ywkrvGACCACCaktry M0406_1.02 wwgGGGGkck |
| Publications: | Badis G, Berger M.F, Philippakis A.A, Talukder S, Gehrke A.R, Jaeger S.A, Chan E.T, Metzler G, Vedenko A, Chen X, Kuznetsov H, Wang C.F, Coburn D, Newburger D.E, Morris Q, Hughes T.R, Bulyk M.L. Diversity and complexity in DNA recognition by transcription factors. Science (New York, N.Y.) 324:1720-3 (2009). [Pubmed] |
| Related annotations: | PaperBLAST |
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