Transcription Factor

Accessions: 1a6y_A (3D-footprint 20231221)
Names: EAR-1, NR1D1_HUMAN, Nuclear receptor subfamily 1 group D member 1, ORPHAN NUCLEAR RECEPTOR NR1D1, Rev-erbA-alpha, V-erbA-related protein 1
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: P20393
Length: 78
Pfam Domains: 2-71 Zinc finger, C4 type (two domains)
Sequence:
(in bold interface residues)
1 LLCKVCGDVASGFHYGVLACEGCKGFFRRSIQQNIQYKRCLKNENCSIVRINRNRCQQCR 60
61 FKKCLSVGMSRDAVRFGR
Interface Residues: 11, 12, 14, 15, 21, 22, 24, 25, 28, 29, 54, 76, 78
3D-footprint Homologues: 6fbq_A, 7wnh_D, 6l6q_B, 3g9m_B, 1a6y_A, 1lo1_A, 4oln_B, 8hbm_B, 5krb_G, 2han_B, 1kb2_B, 2a66_A, 2nll_B, 1lat_A, 7xv6_B, 2ff0_A, 1dsz_A, 4umm_E, 3cbb_A, 8cef_H, 4iqr_B, 2han_A, 1hcq_E, 7prw_B, 5cbx_B, 3g6t_A, 1r4i_A, 5cbz_E, 4tnt_B, 5e69_A, 4hn5_B, 5emc_A
Binding Motifs: 1a6y_A GrCCt
1a6y_AB TGaCCnnnTGACCt
Binding Sites: 1a6y_D
1a6y_C
Publications: Zhao Q, Khorasanizadeh S, Miyoshi Y, Lazar M.A, Rastinejad F. Structural elements of an orphan nuclear receptor-DNA complex. Molecular cell 1:849-61 (1998). [Pubmed]
Related annotations: PaperBLAST

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