Transcription Factor
| Accessions: | T100211_1.02 (CISBP 1.02), P07269 (JASPAR 2024) |
| Names: | PHO2, T100211_1.02;, General regulatory factor 10, PHO2_YEAST, Regulatory protein PHO2 |
| Organisms: | Saccharomyces cerevisiae |
| Libraries: | CISBP 1.02 1, JASPAR 2024 2 1 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed] 2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Notes: | experiment type:PBM, family:Homeodomain |
| Length: | 559 |
| Pfam Domains: | 78-134 Homeobox domain |
| Sequence: (in bold interface residues) | 1 MMEEFSYDHDFNTHFATDLDYLQHDQQQQQQQQHDQQHNQQQQPQPQPIQTQNLEHDHDQ 60 61 HTNDMSASSNASDSGPQRPKRTRAKGEALDVLKRKFEINPTPSLVERKKISDLIGMPEKN 120 121 VRIWFQNRRAKLRKKQHGSNKDTIPSSQSRDIANDYDRGSTDNNLVTTTSTSSIFHDEDL 180 181 TFFDRIPLNSNNNYYFFDICSITVGSWNRMKSGALQRRNFQSIKELRNLSPIKINNIMSN 240 241 ATDLMVLISKKNSEINYFFSAMANNTKILFRIFFPLSSVTNCSLTLETDDDIINSNNTSD 300 301 KNNSNTNNDDDNDDNSNEDNDNSSEDKRNAKDNFGELKLTVTRSPTFAVYFLNNAPDEDP 360 361 NLNNQWSICDDFSEGRQVNDAFVGGSNIPHTLKGLQKSLRFMNSLILDYKSSNEILPTIN 420 421 TAIPTAAVPQQNIAPPFLNTNSSATDSNPNTNLEDSLFFDHDLLSSSITNTNNGQGSNNG 480 481 RQASKDDTLNLLDTTVNSNNNHNANNEENHLAQEHLSNDADIVANPNDHLLSLPTDSELP 540 541 NTPDFLKNTNELTDEHRWI |
| Interface Residues: | 77, 78, 79, 80, 81, 83, 119, 120, 122, 123, 126, 127, 130, 131, 134, 158, 160, 167, 169 |
| 3D-footprint Homologues: | 4j19_B, 6a8r_A, 3d1n_M, 1fjl_B, 5zfz_A, 1ig7_A, 6m3d_C, 3cmy_A, 2lkx_A, 3rkq_B, 5jlw_D, 4cyc_A, 2ld5_A, 2h1k_B, 2hdd_A, 1jgg_B, 5hod_A, 2r5y_A, 4xrs_G, 2hos_A, 1au7_A, 1puf_B, 3l1p_A, 1nk2_P, 1b72_A, 3a01_E, 3lnq_A, 1e3o_C, 1le8_A, 2xsd_C, 7q3o_C, 7xrc_C, 6wig_A, 1puf_A, 8g87_X, 7psx_B, 6es3_K, 5flv_I, 1o4x_A, 1du0_A, 5zjt_E, 4qtr_D, 5esp_A |
| Binding Motifs: | M1132_1.02 TAATAwat MA0356.1 wTAwTw |
| Publications: | Badis G, Chan E.T, van Bakel H, Pena-Castillo L, Tillo D, Tsui K, Carlson C.D, Gossett A.J, Hasinoff M.J, Warren C.L, Gebbia M, Talukder S, Yang A, Mnaimneh S, Terterov D, Coburn D, Li Yeo A, Yeo Z.X, Clarke N.D, Lieb J.D, Ansari A.Z, Nislow C, Hughes T.R. A library of yeast transcription factor motifs reveals a widespread function for Rsc3 in targeting nucleosome exclusion at promoters. Molecular cell 32:878-87 (2008). [Pubmed] |
| Related annotations: | PaperBLAST |
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