Transcription Factor

Accessions: P10244 (JASPAR 2024)
Names: B-Myb, Myb-like protein 2, Myb-related protein B, MYBB_HUMAN
Organisms: Homo sapiens
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Length: 700
Pfam Domains: 31-76 Myb-like DNA-binding domain
34-94 Myb-like DNA-binding domain
83-129 Myb-like DNA-binding domain
86-143 Myb-like DNA-binding domain
136-178 Myb-like DNA-binding domain
138-192 Myb-like DNA-binding domain
451-605 C-myb, C-terminal
Sequence:
(in bold interface residues)
1 MSRRTRCEDLDELHYQDTDSDVPEQRDSKCKVKWTHEEDEQLRALVRQFGQQDWKFLASH 60
61 FPNRTDQQCQYRWLRVLNPDLVKGPWTKEEDQKVIELVKKYGTKQWTLIAKHLKGRLGKQ 120
121 CRERWHNHLNPEVKKSCWTEEEDRIICEAHKVLGNRWAEIAKMLPGRTDNAVKNHWNSTI 180
181 KRKVDTGGFLSESKDCKPPVYLLLELEDKDGLQSAQPTEGQGSLLTNWPSVPPTIKEEEN 240
241 SEEELAAATTSKEQEPIGTDLDAVRTPEPLEEFPKREDQEGSPPETSLPYKWVVEAANLL 300
301 IPAVGSSLSEALDLIESDPDAWCDLSKFDLPEEPSAEDSINNSLVQLQASHQQQVLPPRQ 360
361 PSALVPSVTEYRLDGHTISDLSRSSRGELIPISPSTEVGGSGIGTPPSVLKRQRKRRVAL 420
421 SPVTENSTSLSFLDSCNSLTPKSTPVKTLPFSPSQFLNFWNKQDTLELESPSLTSTPVCS 480
481 QKVVVTTPLHRDKTPLHQKHAAFVTPDQKYSMDNTPHTPTPFKNALEKYGPLKPLPQTPH 540
541 LEEDLKEVLRSEAGIELIIEDDIRPEKQKRKPGLRRSPIKKVRKSLALDIVDEDVKLMMS 600
601 TLPKSLSLPTTAPSNSSSLTLSGIKEDNSLLNQGFLQAKPEKAAVAQKPRSHFTTPAPMS 660
661 SAWKTVACGGTRDQLFMQEKARQLLGRLKPSHTSRTLILS
Interface Residues: 31, 66, 67, 70, 71, 75, 76, 117, 118, 119, 120, 122, 123, 126, 127, 128, 154, 169, 170, 173, 174, 177, 178, 179
3D-footprint Homologues: 3osg_A, 1vfc_A, 1w0t_A, 7c4r_A, 7xur_A, 5eyb_B, 2kdz_A, 6kks_A, 3zqc_A, 1mse_C, 4flw_A, 2xhb_A
Binding Motifs: MA0777.1 rrCCGTTwAACsGyy
Publications: Tang H, Goldberg E. A-MYB (MYBL1) stimulates murine testis-specific Ldhc expression via the cAMP-responsive element (CRE) site. Biol Reprod 86:30 (2012). [Pubmed]
Related annotations: PaperBLAST

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.