Transcription Factor

						

			
Accessions: Q8K1L0 (JASPAR 2024)

			
Names: cAMP-responsive element-binding protein 5, CRE-BPa, CREB-5, CREB5_MOUSE, Cyclic AMP-responsive element-binding protein 5
Organisms: Mus musculus
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Uniprot: Q8K1L0
Length: 357
Pfam Domains:   223-276 Basic region leucine zipper
  226-283 bZIP transcription factor
Sequence: 
(in bold interface residues)		   1 MSMRPVPGSLSSLLHLHNRQRQPMPASMPGTLPNPTMPGSSAVLMPMERQMSVNSSIMGM   60
  61 QGPNLSNPCASPQVQPMHSEAKMRLKAALTHHPAAMSNGNMSTIGHMMEMMGSRQDQTPH  120
 121 HHLHSHPHQHQTLPPHHPYPHQHQHPAHHPHPQPHHQQNHPHHHSHSHLHAHPAHHQTSP  180
 181 HPPLHTGNQAQVSPATQQMQPTQTIQPPQPTGGRRRRVVDEDPDERRRKFLERNRAAATR  240
 241 CRQKRKVWVMSLEKKAEELTQTNMQLQNEVSMLKNEVAQLKQLLLTHKDCPITAMQKESQ  300
 301 GYLSPESSPPASPVPACSQQQVIQHNTITTSSSVSEVVGSSTLSQLTTHRTDLNPIL
Interface Residues: 228, 230, 234, 235, 237, 238, 241, 242
3D-footprint Homologues: 4eot_A, 7x5e_E, 2wt7_B, 2wt7_A, 5vpe_D, 1nwq_C, 6mg1_B, 2dgc_A, 5t01_B, 5vpe_C, 1dh3_C
Binding Motifs: MA0840.1 rATGACGTCAyy
MA0840.2 ATGACGTCAy
			
Publications: Craig JC, Schumacher MA, Mansoor SE, Farrens DL, Brennan RG, Goodman RH. Consensus and variant cAMP-regulated enhancers have distinct CREB-binding properties. J Biol Chem 276:11719-28 (2001). [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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