Transcription Factor

Accessions: T061565_1.02 (CISBP 1.02), Q12531 (JASPAR 2024)
Names: T061565_1.02;, YPR015C, YP015_YEAST
Organisms: Saccharomyces cerevisiae
Libraries: CISBP 1.02 1, JASPAR 2024 2
1 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed]
2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: experiment type:PBM, family:C2H2 ZF
Length: 247
Pfam Domains: 186-207 Zinc finger, C2H2 type
186-204 Zinc-finger of C2H2 type
200-224 Zinc-finger double domain
213-237 Zinc finger, C2H2 type
Sequence:
(in bold interface residues)
1 MWRTKTLESMLCSPMKCSSSNIGGSYAQSSKEVSNTTKREVHLPPCSSIMHAPLTPEINQ 60
61 AALPPPAYHYAPSSLHQTEDPVWRSSPNSIIFSPVIATPQPFPLTFVERQSCCPIYSTAA 120
121 SSYTAQSVPPSMQHFQEENHRAVSNEQYSLPNVHIGQNPGTLLSQTQTDLDLIQKQLRAV 180
181 VKLRKQCPICGKVCSRPSTLRTHYLIHTGDTPFKCTWEHCNKSFNVKSNMLRHLRTHQKK 240
241 IAKKKHQ
Interface Residues: 168, 169, 180, 194, 195, 196, 197, 198, 199, 202, 203, 206, 225, 226, 227, 228, 229, 230, 231, 232, 233, 236
3D-footprint Homologues: 5yel_A, 7w1m_H, 6jnm_A, 3uk3_C, 8cuc_F, 7y3l_A, 7n5w_A, 1tf3_A, 1g2f_F, 5und_A, 5k5i_A, 2jpa_A, 1llm_D, 5v3j_F, 1ubd_C, 8gn3_A, 6blw_A, 5kkq_D, 2kmk_A, 1mey_C, 6u9q_A, 4x9j_A, 1f2i_J, 5kl3_A, 7ysf_A, 6wmi_A, 5ei9_F, 2i13_A, 8ssq_A, 7eyi_G, 4m9v_C, 8h9h_G, 7y3m_I, 6e94_A, 6a57_A, 1tf6_A, 6ml4_A, 2gli_A, 7txc_E, 2wbs_A, 5yj3_D
Binding Motifs: MA0435.1 tkwaraCGTAAATCmtwwhh
M0542_1.02 rrgsgAG
MA0435.2 aCGTAAATCmt
Publications: Newburger D.E, Bulyk M.L. UniPROBE: an online database of protein binding microarray data on protein-DNA interactions. Nucleic acids research 37:D77-82 (2009). [Pubmed]
Related annotations: PaperBLAST

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