Transcription Factor

Accessions: UP00228A (UniPROBE 20160601)
Names: bagpipe homeobox gene 1 homolog (Drosophila), Bagpipe homeobox protein homolog 1, Bapx1, Homeobox protein Nkx-3.2, Nkx3-2, NKX3.2, Nkx3b
Organisms: Mus musculus
Libraries: UniPROBE 20160601 1
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
Uniprot: P97503
Description: bagpipe homeobox gene 1 homolog (Drosophila)
Length: 93
Pfam Domains: 17-73 Homeobox domain
Sequence:
(in bold interface residues)
1 GGVEEEEEPAAPKPRKKRSRAAFSHAQVFELERRFNHQRYLSGPERADLAASLKLTETQV 60
61 KIWFQNRRYKTKRRQMAADLLASAPAAKKVAVK
Interface Residues: 17, 18, 19, 20, 58, 59, 61, 62, 65, 66, 69, 70, 73, 74, 75
3D-footprint Homologues: 2h1k_B, 1puf_A, 6a8r_A, 3cmy_A, 1fjl_B, 5zfz_A, 1zq3_P, 3lnq_A, 2lkx_A, 1jgg_B, 6m3d_C, 3d1n_M, 2ld5_A, 7q3o_C, 6es3_K, 1nk2_P, 1b72_A, 5flv_I, 3l1p_A, 1ig7_A, 5zjt_E, 3a01_E, 5hod_A, 2hdd_A, 5jlw_D, 3rkq_B, 2r5y_A, 4xrs_G, 2hos_A, 7psx_B, 4cyc_A, 1le8_A, 4j19_B, 7xrc_C, 1e3o_C, 1au7_A, 2xsd_C, 6fqp_B, 1o4x_A, 1le8_B, 6fqq_E, 1du0_A, 4qtr_D, 1mnm_C, 1puf_B, 8g87_X, 1k61_B
Binding Motifs: UP00228A_1 mwtawSCACTTAavmay
Binding Sites: AAGTACTT
ACCACTTA
ACTAAGTG
ACTTAAGT
AGCACTTA
AGTACTTA
ATAAGTGG
ATTAAGTG
CACTTAAA
CACTTAAC
CACTTAAG
CCACTTAC
CCACTTAG
CCCACTTA
GCACTTAA
GCCACTTA
GGCACTTA
GGTACTTA
GTACTTAA
TAAGTGGA
Publications: Berger M.F, Badis G, Gehrke A.R, Talukder S, Philippakis A.A, Peña-Castillo L, Alleyne T.M, Mnaimneh S, Botvinnik O.B, Chan E.T, Khalid F, Zhang W, Newburger D, Jaeger S.A, Morris Q.D, Bulyk M.L, Hughes T.R. Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences. Cell 133:1266-76 (2008). [Pubmed]
Related annotations: PaperBLAST

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.