Transcription Factor

Accessions: MYOD1_MOUSE (HOCOMOCO 10), P10085 (JASPAR 2024)
Names: MYOD1_MOUSE
Organisms: Mus musculus
Libraries: HOCOMOCO 10 1, JASPAR 2024 2
1 Kulakovskiy IV, Vorontsov IE, Yevshin IS, Soboleva AV, Kasianov AS, Ashoor H, Ba-Alawi W, Bajic VB, Medvedeva YA, Kolpakov FA, Makeev VJ. HOCOMOCO: expansion and enhancement of the collection of transcription factor binding sites models. Nucleic Acids Res : (2016). [Pubmed]
2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Uniprot: P10085
Length: 318
Pfam Domains: 22-109 Myogenic Basic domain
110-161 Helix-loop-helix DNA-binding domain
190-258 Myogenic determination factor 5
Sequence:
(in bold interface residues)
1 MELLSPPLRDIDLTGPDGSLCSFETADDFYDDPCFDSPDLRFFEDLDPRLVHMGALLKPE 60
61 EHAHFPTAVHPGPGAREDEHVRAPSGHHQAGRCLLWACKACKRKTTNADRRKAATMRERR 120
121 RLSKVNEAFETLKRCTSSNPNQRLPKVEILRNAIRYIEGLQALLRDQDAAPPGAAAFYAP 180
181 GPLPPGRGSEHYSGDSDASSPRSNCSDGMMDYSGPPSGPRRQNGYDTAYYSEAARESRPG 240
241 KSAAVSSLDCLSSIVERISTDSPAAPALLLADAPPESPPGPPEGASLSDTEQGTQTPSPD 300
301 AAPQCPAGSNPNAIYQVL
Interface Residues: 111, 114, 115, 117, 118, 119, 121, 122
3D-footprint Homologues: 2ypa_A, 7z5k_B, 5eyo_A, 5i50_B, 6od3_F, 1am9_A, 2ql2_D, 2ypa_B, 2ql2_A
Binding Motifs: MA0499.1 wsCASCTGyycyy
MYOD1_MOUSE.H10MO.C|M01221 sCAGCTGyyscysyc
Binding Sites: MA0499.1.1
MA0499.1.10
MA0499.1.11
MA0499.1.12
MA0499.1.13
MA0499.1.14
MA0499.1.15
MA0499.1.16
MA0499.1.17
MA0499.1.18
MA0499.1.19
MA0499.1.2
MA0499.1.20
MA0499.1.3
MA0499.1.4
MA0499.1.5
MA0499.1.6
MA0499.1.7
MA0499.1.8
MA0499.1.9
Publications: Cao Y, Yao Z, Sarkar D, Lawrence M, Sanchez G.J, Parker M.H, MacQuarrie K.L, Davison J, Morgan M.T, Ruzzo W.L, Gentleman R.C, Tapscott S.J. Genome-wide MyoD binding in skeletal muscle cells: a potential for broad cellular reprogramming. Developmental cell 18:662-74 (2010). [Pubmed]
Related annotations: PaperBLAST

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.