Transcription Factor

						

			
Accessions: FOSL1 (SMILE-seq 1.0)

			
Names: B2R9B4_HUMAN, cDNA, FLJ94314, highly similar to Homo sapiens FOS-like antigen 1, FOSL1
Organisms: Homo sapiens
Libraries: SMILE-seq 1.0 1
1 Isakova A, Groux R, Imbeault M, Rainer P, Alpern D, Dainese R, Ambrosini G, Trono D, Bucher P, Deplancke B. SMiLE-seq identifies binding motifs of single and dimeric transcription factors. Nat Methods 14:316-322 (2017). [Pubmed]
Uniprot: B2R9B4
Notes: TF family: bZIP
Length: 270
Pfam Domains:   103-162 bZIP transcription factor
  105-157 Basic region leucine zipper
Sequence: 
(in bold interface residues)		   1 MFRDFGEPGPSSGNGGGYGGPAQPPAAAQAAQQKFHLVPSINTMSGSQELQWMVQPHFLG   60
  61 PSSYPRPLTYPQYSPPQPRPGVIRALGPPPGVRRRPCEQISPEEEERRRVRRERNKLAAA  120
 121 KCRNRRKELTDFLQAETDKLEDEKSGLQREIEELQKQKERLELVLEAHRPICKIPEGAKE  180
 181 GDTGSTSGTSSPPAPCRPVPCISLSPGPVLEPEALHTPTLMTTPSLTPFTPSLVFTYPST  240
 241 PEPCASAHRKSSSSSGDPSSDPLGSPTLLA
Interface Residues: 111, 112, 115, 116, 118, 119, 122, 123, 152
3D-footprint Homologues: 7x5e_F, 2wt7_A, 1nwq_C, 6mg1_B, 5vpe_C, 5vpe_D, 4lb5_B
Binding Motifs: JUNB_FOSL1_1 ykrTGAcTMAtmc
JUND_FOSL1_1 rrTGActmAt
JUND_FOSL1_2 rTGACgymay
JUN_FOSL1_1 kkrTGACTCAtmm
JUN_FOSL1_2 rTgACGTcAy
			
Publications: Isakova A, Groux R, Imbeault M, Rainer P, Alpern D, Dainese R, Ambrosini G, Trono D, Bucher P, Deplancke B. SMiLE-seq identifies binding motifs of single and dimeric transcription factors. Nat Methods 14:316-322 (2017). [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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