Transcription Factor
| Accessions: | Hr46 (DrosophilaTF 1.1), T134205_1.02 (CISBP 1.02) |
| Names: | dHR3, HR3_DROME, Nuclear receptor subfamily 1 group F member 4, Probable nuclear hormone receptor HR3, Hr46, T134205_1.02; |
| Organisms: | Drosophila melanogaster |
| Libraries: | DrosophilaTF 1.1 1, CISBP 1.02 2 1 Down T.A, Bergman C.M, Su J, Hubbard T.J. Large-scale discovery of promoter motifs in Drosophila melanogaster. PLoS computational biology 3:e7 (2007). [Pubmed] 2 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed] |
| Uniprot: | P31396 |
| Notes: | experiment type:PBM, family:Nuclear receptor |
| Length: | 487 |
| Pfam Domains: | 50-118 Zinc finger, C4 type (two domains) 281-421 Ligand-binding domain of nuclear hormone receptor |
| Sequence: (in bold interface residues) | 1 MYTQRMFDMWSSVTSKLEAHANNLGQSNVQSPAGQNNSSGSIKAQIEIIPCKVCGDKSSG 60 61 VHYGVITCEGCKGFFRRSQSSVVNYQCPRNKQCVVDRVNRNRCQYCRLQKCLKLGMSRDA 120 121 VKFGRMSKKQREKVEDEVRFHRAQMRAQSDAAPDSSVYDTQTPSSSDQLHHNNYNSYSGG 180 181 YSNNEVGYGSPYGYSASVTPQQTMQYDISADYVDSTTYEPRSTIIDPEFISHADGDINDV 240 241 LIKTLAEAHANTNTKLEAVHDMFRKQPDVSRILYYKNLGQEELWLDCAEKLTQMIQNIIE 300 301 FAKLIPGFMRLSQDDQILLLKTGSFELAIVRMSRLLDLSQNAVLYGDVMLPQEAFYTSDS 360 361 EEMRLVSRIFQTAKSIAELKLTETELALYQSLVLLWPERNGVRGNTEIQRLFNLSMNAIR 420 421 QELETNHAPLKGDVTVLDTLLNNIPNFRDISILHMESLSKFKLQHPNVVFPALYKELFSI 480 481 DSQQDLT |
| Interface Residues: | 59, 60, 62, 63, 69, 70, 72, 73, 76, 77, 101, 123, 125, 132, 134 |
| 3D-footprint Homologues: | 6fbq_A, 7wnh_D, 6l6q_B, 3g9m_B, 1a6y_A, 1lo1_A, 4oln_B, 8hbm_B, 5krb_G, 2han_B, 1kb2_B, 2a66_A, 2nll_B, 1lat_A, 7xv6_B, 2ff0_A, 1dsz_A, 4umm_E, 3cbb_A, 8cef_H, 4iqr_B, 2han_A, 1hcq_E, 5cbz_E, 4tnt_B, 5e69_A, 4hn5_B, 5emc_A, 7prw_B, 5cbx_B, 3g6t_A, 1r4i_A |
| Binding Motifs: | Hr46 GGGTCA M1469_1.02 kTGACCyc |
| Publications: | Lam G.T, Jiang C, Thummel C.S. Coordination of larval and prepupal gene expression by the DHR3 orphan receptor during Drosophila metamorphosis. Development (Cambridge, England) 124:1757-69 (1997). [Pubmed] |
| Related annotations: | PaperBLAST |
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.