Transcription Factor
| Accessions: | Q08605 (JASPAR 2024) |
| Names: | Adh transcription factor 2, GAF, GAGA factor, GAGA_DROME, Neural conserved at 70F, Transcription factor GAGA, Trithorax-like protein |
| Organisms: | Drosophila melanogaster |
| Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Uniprot: | Q08605 |
| Length: | 581 |
| Pfam Domains: | 25-119 BTB/POZ domain 319-372 GAGA factor |
| Sequence: (in bold interface residues) | 1 MSLPMNSLYSLTWGDYGTSLVSAIQLLRCHGDLVDCTLAAGGRSFPAHKIVLCAASPFLL 60 61 DLLKNTPCKHPVVMLAGVNANDLEALLEFVYRGEVSVDHAQLPSLLQAAQCLNIQGLAPQ 120 121 TVTKDDYTTHSIQLQHMIPQHHDQDQLIATIATAPQQTVHAQVVEDIHHQGQILQATTQT 180 181 NAAGQQQTIVTTDAAKHDQAVIQAFLPARKRKPRVKKMSPTAPKISKVEGMDTIMGTPTS 240 241 SHGSGSVQQVLGENGAEGQLLSSTPIIKSEGQKVETIVTMDPNNMIPVTSANAATGEITP 300 301 AQGATGSSGGNTSGVLSTPKAKRAKHPPGTEKPRSRSQSEQPATCPICYAVIRQSRNLRR 360 361 HLELRHFAKPGVKKEKKTTSGKKSSSGSSGSGSGALSSSGSVPQVQTVQSLHTLQGVQVK 420 421 KDPDAQQQQQQQQQQQQQQQQAMTVSGATGGQVQQQVQQVQQQVQQQQQQQQQQQQQLQH 480 481 HQIIDSSGNITTATTSAQAAAAAQQQAAGQQQQLVAQSDGSESGAPLSIAQVQTLQGHQI 540 541 IGNLNQVNMTDFQQQQPQQQQQQQQQQQQQQQQQQQTQQTL |
| Interface Residues: | 323, 325, 327, 328, 329, 332, 333, 336, 339, 340, 354, 356, 357, 358, 359, 360, 361 |
| 3D-footprint Homologues: | 1yuj_A, 4m9v_C, 3uk3_C, 7ysf_A |
| Binding Motifs: | MA0205.1 yykCTCTCty MA0205.2 rrrAGAGAGArr MA0205.3 rAGAGAGAr |
| Binding Sites: | MA0205.1.1 MA0205.1.10 MA0205.1.11 MA0205.1.12 MA0205.1.13 MA0205.1.14 MA0205.1.15 MA0205.1.16 MA0205.1.17 MA0205.1.18 MA0205.1.19 MA0205.1.2 MA0205.1.20 MA0205.1.3 MA0205.1.4 MA0205.1.5 MA0205.1.6 MA0205.1.7 MA0205.1.8 MA0205.1.9 MA0205.2.1 MA0205.2.10 MA0205.2.11 MA0205.2.12 MA0205.2.13 MA0205.2.14 MA0205.2.15 MA0205.2.16 MA0205.2.17 MA0205.2.18 MA0205.2.19 MA0205.2.2 MA0205.2.20 MA0205.2.3 MA0205.2.4 MA0205.2.5 MA0205.2.6 MA0205.2.7 MA0205.2.8 MA0205.2.9 MA0205.3.1 / MA0205.3.19 MA0205.3.10 MA0205.3.11 / MA0205.3.16 MA0205.3.12 MA0205.3.13 MA0205.3.14 MA0205.3.15 MA0205.3.17 MA0205.3.18 MA0205.3.2 / MA0205.3.20 / MA0205.3.3 MA0205.3.4 / MA0205.3.9 MA0205.3.5 MA0205.3.6 MA0205.3.7 MA0205.3.8 |
| Publications: | Bergman C.M, Carlson J.W, Celniker S.E. Drosophila DNase I footprint database: a systematic genome annotation of transcription factor binding sites in the fruitfly, Drosophila melanogaster. Bioinformatics (Oxford, England) 21:1747-9 (2005). [Pubmed] Omelina ES, Baricheva EM, Oshchepkov DY, Merkulova TI. Analysis and recognition of the GAGA transcription factor binding sites in Drosophila genes. Comput Biol Chem 35:363-70 (2011). [Pubmed] |
| Related annotations: | PaperBLAST |
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