Transcription Factor

Accessions: Q91ZD1 (JASPAR 2024)
Names: OSR2_MOUSE
Organisms: Mus musculus
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Uniprot: Q91ZD1
Length: 312
Pfam Domains: 172-189 C2H2-type zinc finger
172-194 Zinc finger, C2H2 type
172-194 C2H2-type zinc finger
186-210 Zinc-finger double domain
199-220 C2H2-type zinc finger
200-222 Zinc finger, C2H2 type
200-222 C2H2-type zinc finger
214-237 Zinc-finger double domain
228-252 C2H2-type zinc finger
228-250 Zinc finger, C2H2 type
245-266 Zinc-finger double domain
255-274 C2H2-type zinc finger
256-278 Zinc finger, C2H2 type
256-278 C2H2-type zinc finger
270-294 Zinc-finger double domain
284-294 C2H2-type zinc finger
284-306 Zinc finger, C2H2 type
284-306 C2H2-type zinc finger
Sequence:
(in bold interface residues)
1 MGSKALPAPIPLHPSLQLTNYSFLQAVNTFPAAVDHLQGLYGLSAVQTMHMNHWTLGYPS 60
61 VHEITRSTITEMAAAQGLVDARFPFPSLPFATHLFHPKQGAIAHVLPALHKDRPRFDFAN 120
121 LAVAATQEDPPKMGDLSKLSPGLGSPISGLSKLNPDRKPSRGRLPSKTKKEFICKFCGRH 180
181 FTKSYNLLIHERTHTDERPYTCDICHKAFRRQDHLRDHRYIHSKEKPFKCQECGKGFCQS 240
241 RTLAVHKTLHMQESPHKCPTCGRTFNQRSNLKTHLLTHTDIKPYSCEQCGKVFRRNCDLR 300
301 RHSLTHTPRQNF
Interface Residues: 44, 46, 152, 153, 154, 155, 182, 183, 184, 185, 186, 188, 189, 196, 197, 200, 210, 211, 212, 213, 214, 216, 217, 219, 220, 221, 223, 238, 239, 240, 241, 242, 243, 245, 246, 247, 249, 266, 267, 268, 269, 270, 271, 272, 273, 274, 287, 290, 294, 295, 296, 297, 298, 300, 301
3D-footprint Homologues: 4kdp_B, 6kdb_D, 5v3j_F, 8cuc_F, 1tf3_A, 3uk3_C, 7y3l_A, 7n5w_A, 2gli_A, 1llm_D, 6u9q_A, 6blw_A, 5kkq_D, 7w1m_H, 4x9j_A, 5kl3_A, 8ssu_A, 1g2f_F, 5ei9_F, 1tf6_A, 5und_A, 8h9h_G, 7eyi_G, 7y3m_I, 2lt7_A, 2i13_A, 7ysf_A, 6wmi_A, 6e94_A, 1yuj_A, 2kmk_A, 5k5i_A, 2wbs_A, 8ssq_A, 1f2i_J, 5yel_A, 6ml4_A, 2jpa_A, 1ubd_C, 6jnm_A, 1mey_C, 4m9v_C, 6a57_A, 7txc_E, 2drp_D, 8gn3_A, 6fbq_A, 5yj3_D
Binding Motifs: PB0051.1 wwrwACrGTAGCwmwr
PB0155.1 rhttGCTACywrmwym
Publications: Badis G, Berger M.F, Philippakis A.A, Talukder S, Gehrke A.R, Jaeger S.A, Chan E.T, Metzler G, Vedenko A, Chen X, Kuznetsov H, Wang C.F, Coburn D, Newburger D.E, Morris Q, Hughes T.R, Bulyk M.L. Diversity and complexity in DNA recognition by transcription factors. Science (New York, N.Y.) 324:1720-3 (2009). [Pubmed]
Related annotations: PaperBLAST

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