Transcription Factor
| Accessions: | O46339 (JASPAR 2024) |
| Names: | Homeobox protein dorsotonals, Homeobox protein homothorax, HTH_DROME |
| Organisms: | Drosophila melanogaster |
| Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Uniprot: | O46339 |
| Length: | 487 |
| Pfam Domains: | 367-422 Homeobox domain 383-422 Homeobox KN domain |
| Sequence: (in bold interface residues) | 1 MAQPRYDDGLHGYGMDSGAAAAAMYDPHAGHRPPGLQGLPSHHSPHMTHAAAAAATVGMH 60 61 GYHSGAGGHGTPSHVSPVGNHLMGAIPEVHKRDKDAIYEHPLFPLLALIFEKCELATCTP 120 121 REPGVQGGDVCSSESFNEDIAMFSKQIRSQKPYYTADPEVDSLMVQAIQVLRFHLLELEK 180 181 VHELCDNFCHRYISCLKGKMPIDLVIDERDTTKPPELGSANGEGRSNADSTSHTDGASTP 240 241 DVRPPSSSLSYGGAMNDDARSPGAGSTPGPLSQQPPALDTSDPDGKFLSSLNPSELTYDG 300 301 RWCRREWSSPADARNADASRRLYSSVFLGSPDNFGTSASGDASNASIGSGEGTGEEDDDA 360 361 SGKKNQKKRGIFPKVATNILRAWLFQHLTHPYPSEDQKKQLAQDTGLTILQVNNWFINAR 420 421 RRIVQPMIDQSNRAVYTPHPGPSGYGHDAMGYMMDSQAHMMHRPPGDPGFHQGYPHYPPA 480 481 EYYGQHL |
| Interface Residues: | 366, 368, 369, 371, 413, 414, 417, 418, 419, 421, 422 |
| 3D-footprint Homologues: | 5zfz_A, 6fqp_B, 2d5v_B, 1mnm_C, 1puf_B, 4j19_B, 7q3o_C, 1le8_A, 5hod_A, 6fqq_E, 1le8_B, 3cmy_A, 1fjl_B, 4xrm_B, 6a8r_A, 3lnq_A, 1k61_B, 4xrs_G, 3rkq_B |
| Binding Motifs: | MA0227.1 TGACAk |
| Binding Sites: | MA0227.1.1 MA0227.1.10 MA0227.1.11 MA0227.1.12 MA0227.1.13 MA0227.1.14 MA0227.1.15 MA0227.1.16 MA0227.1.17 MA0227.1.18 MA0227.1.19 MA0227.1.2 MA0227.1.20 MA0227.1.3 MA0227.1.4 MA0227.1.5 MA0227.1.6 MA0227.1.7 MA0227.1.8 MA0227.1.9 |
| Publications: | Noyes M.B, Meng X, Wakabayashi A, Sinha S, Brodsky M.H, Wolfe S.A. A systematic characterization of factors that regulate Drosophila segmentation via a bacterial one-hybrid system. Nucleic acids research 36:2547-60 (2008). [Pubmed] |
| Related annotations: | PaperBLAST |
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.