Transcription Factor
| Accessions: | Q6NKN9 (JASPAR 2024), T04726 (AthalianaCistrome v4_May2016) |
| Names: | AtbHLH74, Basic helix-loop-helix protein 74, BH074_ARATH, bHLH 74, bHLH transcription factor bHLH074, Protein ACTIVATOR FOR CELL ELONGATION 2, Transcription factor bHLH74, Transcription factor EN 90, AT1G10120, bHLH74, T04726; |
| Organisms: | Arabidopsis thaliana |
| Libraries: | JASPAR 2024 1, AthalianaCistrome v4_May2016 2 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] 2 O'Malley RC, Huang SS, Song L, Lewsey MG, Bartlett A, Nery JR, Galli M, Gallavotti A, Ecker JR. Cistrome and Epicistrome Features Shape the Regulatory DNA Landscape. Cell 165:1280-92 (2016). [Pubmed] |
| Notes: | ecotype:Col-0, experiment type: ampDAP-seq, experiment type: ampDAP-seq (methyl-cytosines removed by PCR), experiment type: DAP-seq, family:bHLH |
| Length: | 366 |
| Pfam Domains: | 215-263 Helix-loop-helix DNA-binding domain |
| Sequence: (in bold interface residues) | 1 MGGESNEGGEMGFKHGDDESGGISRVGITSMPLYAKADPFFSSADWDPVVNAAAAGFSSS 60 61 HYHPSMAMDNPGMSCFSHYQPGSVSGFAADMPASLLPFGDCGGGQIGHFLGSDKKGERLI 120 121 RAGESSHEDHHQVSDDAVLGASPVGKRRLPEAESQWNKKAVEEFQEDPQRGNDQSQKKHK 180 181 NDQSKETVNKESSQSEEAPKENYIHMRARRGQATNSHSLAERVRREKISERMRLLQELVP 240 241 GCNKITGKAVMLDEIINYVQSLQQQVEFLSMKLATVNPEINIDIDRILAKDLLQSRDRNT 300 301 PTLGLNPFAGFQGNIPNLSATTNPQYNPLPQTTLESELQNLYQMGFVSNPSTMSSFSPNG 360 361 RLKPEL |
| Interface Residues: | 217, 218, 220, 221, 224, 225, 248 |
| 3D-footprint Homologues: | 6g1l_A, 1a0a_B, 5gnj_I, 7d8t_A, 4h10_A, 5nj8_D, 7ssa_L, 4zpk_A, 5v0l_A, 7xi3_A, 5eyo_A, 8osl_P |
| Binding Motifs: | M0172 / MA1360.1 cgtgarwrkCACGTGmsaycw M0179 CACGTGAy MA1360.2 kwvbCACGTGvywh MA1360.3 CACGTG |
| Binding Sites: | MA1360.3.1 / MA1360.3.10 / MA1360.3.11 / MA1360.3.12 / MA1360.3.13 / MA1360.3.14 / MA1360.3.15 / MA1360.3.16 / MA1360.3.17 / MA1360.3.18 / MA1360.3.19 / MA1360.3.2 / MA1360.3.20 / MA1360.3.3 / MA1360.3.4 / MA1360.3.5 / MA1360.3.6 / MA1360.3.7 / MA1360.3.8 / MA1360.3.9 MA1360.2.3 MA1360.2.11 MA1360.2.12 MA1360.2.13 MA1360.2.19 MA1360.2.20 MA1360.2.4 MA1360.2.10 MA1360.2.1 / MA1360.2.2 MA1360.2.14 MA1360.2.15 MA1360.2.16 MA1360.2.17 MA1360.2.18 MA1360.2.5 MA1360.2.6 MA1360.2.7 MA1360.2.8 MA1360.2.9 |
| Publications: | Fernández-Calvo P, Chini A, Fernández-Barbero G, Chico J.M, Gimenez-Ibanez S, Geerinck J, Eeckhout D, Schweizer F, Godoy M, Franco-Zorrilla J.M, Pauwels L, Witters E, Puga M.I, Paz-Ares J, Goossens A, Reymond P, De Jaeger G, Solano R. The Arabidopsis bHLH transcription factors MYC3 and MYC4 are targets of JAZ repressors and act additively with MYC2 in the activation of jasmonate responses. The Plant cell 23:701-15 (2011). [Pubmed] |
| Related annotations: | PaperBLAST |
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