Transcription Factor

Accessions: Q8WYK2 (JASPAR 2024)
Names: JDP2_HUMAN
Organisms: Homo sapiens
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Uniprot: Q8WYK2
Length: 163
Pfam Domains: 70-128 bZIP transcription factor
71-124 Basic region leucine zipper
Sequence:
(in bold interface residues)
1 MMPGQIPDPSVTTGSLPGLGPLTGLPSSALTVEELKYADIRNLGAMIAPLHFLEVKLGKR 60
61 PQPVKSELDEEEERRKRRREKNKVAAARCRNKKKERTEFLQRESERLELMNAELKTQIEE 120
121 LKQERQQLILMLNRHRPTCIVRTDSVKTPESEGNPLLEQLEKK
Interface Residues: 41, 43, 78, 79, 82, 83, 85, 86, 89, 90, 93
3D-footprint Homologues: 4pd2_A, 6fl1_A, 6rnr_A, 7x5e_E, 1skn_P, 7x5e_F, 2wt7_A, 2wt7_B, 6mg1_B, 1nwq_C, 5t01_B, 5vpe_C, 5vpe_D
Binding Motifs: MA0655.1 ATGASTCAT
MA0656.1 gATGACGTCAyc
MA0656.2 ATGACGTCAy
Publications: Aronheim A., Zandi E., Hennemann H., Elledge S. J., Karin M. Isolation of an AP-1 repressor by a novel method for detecting protein-protein interactions.. Mol. Cell. Biol. 17:3094-3102 (1997). [Pubmed]
Related annotations: PaperBLAST

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