Transcription Factor
| Accessions: | Cf2 (DrosophilaTF 1.1), P20385 (JASPAR 2024) |
| Names: | CF2_DROME |
| Organisms: | Drosophila melanogaster |
| Libraries: | DrosophilaTF 1.1 1, JASPAR 2024 2 1 Down T.A, Bergman C.M, Su J, Hubbard T.J. Large-scale discovery of promoter motifs in Drosophila melanogaster. PLoS computational biology 3:e7 (2007). [Pubmed] 2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Uniprot: | P20385 |
| Length: | 510 |
| Pfam Domains: | 366-388 Zinc finger, C2H2 type 366-388 C2H2-type zinc finger 381-412 Zinc-finger double domain 400-416 C2H2-type zinc finger 401-423 Zinc finger, C2H2 type 401-420 C2H2-type zinc finger 416-439 Zinc-finger double domain 429-451 C2H2-type zinc finger 429-438 C2H2-type zinc finger 429-451 Zinc finger, C2H2 type 444-467 Zinc-finger double domain 457-479 Zinc finger, C2H2 type 457-479 C2H2-type zinc finger 457-467 C2H2-type zinc finger 472-496 Zinc-finger double domain 484-504 C2H2-type zinc finger 485-508 Zinc finger, C2H2 type 485-508 C2H2-type zinc finger |
| Sequence: (in bold interface residues) | 1 MIKSTTNPQEQRLPRPEDQSPAPPPPPPSSATTSTAAPATPTHQVATVIANMDTLKTAFL 60 61 PNLSMDPNVHVSPHYCPMCHQQFERPQHVADHMQLCHGITLNAQGAIATLDGGHPQAQQH 120 121 PKLSHPCFNCDEKFGNAVDLDEHHRLAHQTPAFLSRCLMCSIYGIHSATQQPNEYKCTQC 180 181 GSICTTAMLAAGQQGFMEQQEAAVTPDDQLPAMAPRDMRLTPEEQHHQQQLQAEHHHQQQ 240 241 HQQQQQQQQQQQELLEQQQREMQEQAQQQQVHHHQQDQDLAGDQVALKVPPLTVKLNKNA 300 301 NGGAIVSHPQVIIKEEPLSLSDSGDVVNSVPVYAIQANPGVPAPASSGVLVGTQTVPADL 360 361 AHKIRHKCPDCPKTFKTPGTLAMHRKIHTGEADATPKERPYTCSYCGKSFTQSNTLKQHT 420 421 RIHTGEKPFRCGYCGRAFTVKDYLNKHLTTHTGEKPFHCGYCEKSFSVKDYLTKHIRTHT 480 481 GEKPYTCPYCDKRFTQRSALTVHTTKLHPL |
| Interface Residues: | 233, 237, 240, 241, 245, 353, 376, 377, 378, 379, 380, 383, 387, 401, 411, 412, 413, 414, 415, 417, 418, 419, 420, 421, 422, 424, 439, 440, 441, 442, 443, 444, 445, 446, 447, 467, 468, 469, 470, 471, 472, 473, 474, 495, 496, 497, 498, 499, 501, 502, 506 |
| 3D-footprint Homologues: | 4eot_A, 5yel_A, 7w1m_H, 5v3j_F, 7n5w_A, 8ssq_A, 5kkq_D, 8ssu_A, 6wmi_A, 8h9h_G, 7eyi_G, 2i13_A, 2kmk_A, 8cuc_F, 7y3l_A, 5k5i_A, 5und_A, 6ml4_A, 4x9j_A, 1mey_C, 6blw_A, 1f2i_J, 6u9q_A, 5ei9_F, 8gn3_A, 5kl3_A, 2gli_A, 1g2f_F, 4m9v_C, 2lt7_A, 6e94_A, 7ysf_A, 2jpa_A, 1ubd_C, 6jnm_A, 3uk3_C, 1tf3_A, 1tf6_A, 2wbs_A, 7txc_E, 5yj3_D, 6a57_A, 1llm_D, 5k5l_F, 2drp_D, 7y3m_I, 8gh6_A |
| Binding Motifs: | Cf2 rTATATrTr MA0015.1 rTATATrTry MA0015.2 rTATATrTr |
| Binding Sites: | Cf2_1 Cf2_10 Cf2_11 Cf2_12 Cf2_13 Cf2_14 Cf2_15 Cf2_16 Cf2_17 Cf2_18 Cf2_19 Cf2_2 Cf2_20 Cf2_21 Cf2_22 Cf2_23 Cf2_24 Cf2_25 Cf2_26 Cf2_27 Cf2_28 Cf2_29 Cf2_3 Cf2_30 Cf2_31 Cf2_32 Cf2_33 Cf2_34 Cf2_35 Cf2_36 Cf2_37 Cf2_38 Cf2_39 Cf2_4 Cf2_40 Cf2_41 Cf2_42 Cf2_43 Cf2_44 Cf2_45 Cf2_46 Cf2_47 Cf2_48 Cf2_49 Cf2_5 Cf2_50 Cf2_51 Cf2_52 Cf2_53 Cf2_54 Cf2_55 Cf2_56 Cf2_57 Cf2_58 Cf2_59 Cf2_6 Cf2_60 Cf2_61 Cf2_62 Cf2_63 Cf2_64 Cf2_65 Cf2_66 Cf2_67 Cf2_68 Cf2_69 Cf2_7 Cf2_70 Cf2_71 Cf2_72 Cf2_73 Cf2_74 Cf2_75 Cf2_76 Cf2_77 Cf2_78 Cf2_79 Cf2_8 Cf2_80 Cf2_9 MA0015.1.1 MA0015.1.10 MA0015.1.11 MA0015.1.12 MA0015.1.13 MA0015.1.14 MA0015.1.15 MA0015.1.16 MA0015.1.17 MA0015.1.18 MA0015.1.19 MA0015.1.2 MA0015.1.20 MA0015.1.3 MA0015.1.4 MA0015.1.5 MA0015.1.6 MA0015.1.7 MA0015.1.8 MA0015.1.9 MA0015.2.1 MA0015.2.10 MA0015.2.11 MA0015.2.12 MA0015.2.13 MA0015.2.14 MA0015.2.15 MA0015.2.16 MA0015.2.17 MA0015.2.18 MA0015.2.19 MA0015.2.2 MA0015.2.20 MA0015.2.3 MA0015.2.4 MA0015.2.5 MA0015.2.6 MA0015.2.7 MA0015.2.8 MA0015.2.9 |
| Publications: | Gogos J. A., Hsu T., Bolton J., Kafatos F. C. Sequence discrimination by alternatively spliced isoforms of a DNA binding Zinc finger domain. Science 257:1951-1955 (1992). [Pubmed] |
| Related annotations: | PaperBLAST |
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.