Transcription Factor
| Accessions: | P32114 (JASPAR 2024) |
| Names: | PAX2_MOUSE |
| Organisms: | Mus musculus |
| Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Uniprot: | P32114 |
| Length: | 414 |
| Pfam Domains: | 16-139 'Paired box' domain 304-412 Paired-box protein 2 C terminal |
| Sequence: (in bold interface residues) | 1 MDMHCKADPFSAMHRHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVS 60 61 HGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLAE 120 121 GICDNDTVPSVSSINRIIRTKVQQPFHPTPDGAGTGVTAPGHTIVPSTASPPVSSASNDP 180 181 VGSYSINGILGIPRSNGEKRKREEVEVYTDPAHIRGGGGLHLVWTLRDVSEGSVPNGDSQ 240 241 SGVDSLRKHLRADTFTQQQLEALDRVFERPSYPDVFQASEHIKSEQGNEYSLPALTPGLD 300 301 EVKSSLSASANPELGSNVSGTQTYPVVTGRDMTSTTLPGYPPHVPPTGQGSYPTSTLAGM 360 361 VPGSEFSGNPYSHPQYTAYNEAWRFSNPALLSSPYYYSAAPRGSAPAAAAYDRH |
| Interface Residues: | 28, 60, 61, 63, 65, 66, 82, 85, 88, 130, 131, 132, 133, 135, 136, 139 |
| 3D-footprint Homologues: | 1pdn_C, 6pax_A, 1k78_A |
| Binding Motifs: | MA0067.1 wgTCAykb |
| Binding Sites: | MA0067.1.1 MA0067.1.10 MA0067.1.11 MA0067.1.12 MA0067.1.13 MA0067.1.14 MA0067.1.15 MA0067.1.16 MA0067.1.17 MA0067.1.18 MA0067.1.19 MA0067.1.2 MA0067.1.20 MA0067.1.3 MA0067.1.4 MA0067.1.5 MA0067.1.6 MA0067.1.7 / MA0067.1.8 MA0067.1.9 |
| Publications: | Epstein J., Cai J., Glaser T., Jepeal L., Maas R. Identification of a Pax paired domain recognition sequence and evidence for DNA-dependent conformational changes. J. Biol. Chem. 269:8355-8361 (1994). [Pubmed] |
| Related annotations: | PaperBLAST |
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