Transcription Factor
| Accessions: | P63955 (JASPAR 2024) |
| Names: | EC 1.1.1.17, Mannitol-1-phosphate 5-dehydrogenase, MTLD_STAAM |
| Organisms: | Mus musculus |
| Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Uniprot: | P63955 |
| Length: | 368 |
| Pfam Domains: | 1-119 Mannitol dehydrogenase Rossmann domain 141-356 Mannitol dehydrogenase C-terminal domain |
| Sequence: (in bold interface residues) | 1 MKAVHFGAGNIGRGFIGYILADNNVKVTFADVNEEIINALAHDHQYDVILADESKTTTRV 60 61 NNVDAINSMQPSEALKQAILEADIITTAVGVNILPIIAKSFAPFLKEKTNHVNIVACENA 120 121 IMATDTLKKAVLDITGPLGNNIHFANSAVDRIVPLQKNENILDVMVEPFYEWVVEKDAWY 180 181 GPELNHIKYVDDLTPYIERKLLTVNTGHAYLAYAGKFAGKATVLDAVKDSSIEAGLRRVL 240 241 AETSQYITNEFDFTEAEQAGYVEKIIDRFNNSYLSDEVTRVGRGTLRKIGPKDRIIKPLT 300 301 YLYNKDLERTGLLNTAALLLKYDDTADQETVEKNNYIKEHGLKAFLSEYAKVDDGLADEI 360 361 IEAYNSLS |
| Interface Residues: | 138, 147, 148, 149, 151, 155, 174, 177, 178, 179, 181, 183, 185, 205, 206, 222, 224, 226, 228, 230, 233, 234, 238, 239, 240, 245, 248, 273, 275, 277, 354 |
| 3D-footprint Homologues: | 3spd_A, 1mow_A, 5h3r_A, 1a31_A, 5t2o_A, 5t8d_A, 5thg_A, 5t2n_A, 7rcf_A |
| Binding Motifs: | PH0150.1 wrtwATTAATkArkyc |
| Publications: | Berger M.F, Badis G, Gehrke A.R, Talukder S, Philippakis A.A, Peña-Castillo L, Alleyne T.M, Mnaimneh S, Botvinnik O.B, Chan E.T, Khalid F, Zhang W, Newburger D, Jaeger S.A, Morris Q.D, Bulyk M.L, Hughes T.R. Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences. Cell 133:1266-76 (2008). [Pubmed] |
| Related annotations: | PaperBLAST |
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