Transcription Factor
| Accessions: | T144605_1.02 (CISBP 1.02), Q8CGW4 (JASPAR 2024) |
| Names: | Sox30, T144605_1.02;, SOX30_MOUSE |
| Organisms: | Mus musculus |
| Libraries: | CISBP 1.02 1, JASPAR 2024 2 1 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed] 2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Notes: | experiment type:PBM, family:Sox |
| Length: | 782 |
| Pfam Domains: | 366-433 HMG (high mobility group) box 367-429 Domain of unknown function (DUF1898) |
| Sequence: (in bold interface residues) | 1 MERARPEPPPPPPPPPRQPPRPTPPRPLRPAPPAQPVEAATFRAAAAERSQSPSAQATAA 60 61 MAAVASSCGEAAAAGAQAAGTRRLLQVKPEQVLLLPPGGPGVPPAPDEGAAAAAAAAAAA 120 121 ASSAQARLLQLRPELLLLPPQSAADGGPCRPELHPMQPRTLLVKAEKQELGAGLDLSVGS 180 181 RRTTEAGPRASRAAKLDGTGKALDGRRSDEKKAKLEAEEAPRDALKGGEGKSLLAIGEGV 240 241 IKTEEPDRPRDDCRLGTEATSNGLVHSSKEAILAQPPSAFGPHQQDLRFPLTLHTVPPGA 300 301 RIQFQGPPPSELIRLSKVPLTPVPIKMQSLLEPSVKIETKDVPLTVLPSDAGIPDTPFSK 360 361 DRNGHVKRPMNAFMVWARIHRPALAKANPAANNAEISVQLGLEWNKLSEEQKKPYYDEAQ 420 421 KIKEKHREEFPGWVYQPRPGKRKRFPLSVSNVFSGTTQNIISTNPTTIYPYRSPTYSVVI 480 481 PGLQNTITHPVGEAPPAIQLPTPAVQRPSPITLFQPSVSSTGPVAVPPPSLTPRPSLPPQ 540 541 RFSGPSQTDIHRLPSGSSRSVKRSTPGSLESTTRIPAGASTAHARFATSPIQPPKEYASV 600 601 STCPRSTPIPPATPIPHSHVYQPPPLGHPATLFGTPPRFSFHHPYFLPGPHYFPSSTCPY 660 661 SRPPFGYGNFPSSMPECLGYYEDRYQKHEAIFSALNRDYPFRDYPDEHTHSEDSRSCESM 720 721 DGPPYYSSHGHGGEEYLNAMPTLDIGALENVFTAPASAPSGVQQVNVTDSDEEEEEKVLR 780 781 NL |
| Interface Residues: | 368, 371, 373, 374, 377, 381, 392, 393, 394, 397, 435, 437, 439, 442 |
| 3D-footprint Homologues: | 3u2b_C, 1o4x_B, 7m5w_A, 3f27_D, 4s2q_D, 1qrv_A, 3tmm_A, 4y60_C, 2gzk_A, 1j5n_A, 6jrp_D, 2lef_A, 1hry_A, 3tq6_B, 7zie_A |
| Binding Motifs: | PB0070.1 rwdgAACAATkraayt PB0174.1 tmwgATTATAATmcgs M1589_1.02 rcrrrAyAAT |
| Publications: | Badis G, Berger M.F, Philippakis A.A, Talukder S, Gehrke A.R, Jaeger S.A, Chan E.T, Metzler G, Vedenko A, Chen X, Kuznetsov H, Wang C.F, Coburn D, Newburger D.E, Morris Q, Hughes T.R, Bulyk M.L. Diversity and complexity in DNA recognition by transcription factors. Science (New York, N.Y.) 324:1720-3 (2009). [Pubmed] |
| Related annotations: | PaperBLAST |
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