Transcription Factor

Accessions: Q9LK48 (JASPAR 2024), T15315 (AthalianaCistrome v4_May2016)
Names: AtbHLH77, Basic helix-loop-helix protein 77, BH077_ARATH, bHLH 77, bHLH transcription factor bHLH077, Protein ACTIVATOR FOR CELL ELONGATION 3, Transcription factor bHLH77, Transcription factor EN 87, AT3G23690, bHLH77, T15315;
Organisms: Arabidopsis thaliana
Libraries: JASPAR 2024 1, AthalianaCistrome v4_May2016 2
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
2 O'Malley RC, Huang SS, Song L, Lewsey MG, Bartlett A, Nery JR, Galli M, Gallavotti A, Ecker JR. Cistrome and Epicistrome Features Shape the Regulatory DNA Landscape. Cell 165:1280-92 (2016). [Pubmed]
Notes: ecotype:Col-0, experiment type: DAP-seq, family:bHLH
Length: 371
Pfam Domains: 201-248 Helix-loop-helix DNA-binding domain
Sequence:
(in bold interface residues)
1 MNMDKETEQTLNYLPLGQSDPFGNGNEGTIGDFLGRYCNNPQEISPLTLQSFSLNSQISE 60
61 NFPISGGIRFPPYPGQFGSDREFGSQPTTQESNKSSLLDPDSVSDRVHTTKSNSRKRKSI 120
121 PSGNGKESPASSSLTASNSKVSGENGGSKGGKRSKQDVAGSSKNGVEKCDSKGDNKDDAK 180
181 PPEAPKDYIHVRARRGQATDSHSLAERARREKISERMTLLQDLVPGCNRITGKAVMLDEI 240
241 INYVQSLQRQVEFLSMKLATVNPRMEFNANASLSTEMIQPGESLTQSLYAMACSEQRLPS 300
301 AYYSLGKNMPRFSDTQFPSNDGFVHTETPGFWENNDLQSIVQMGFGDILQQQSNNNNNNC 360
361 SEPTLQMKLEP
Interface Residues: 202, 203, 205, 206, 209, 210, 233
3D-footprint Homologues: 7ssa_L, 4zpk_A, 5v0l_A, 1a0a_B, 7xi3_A, 5eyo_A, 6g1l_A, 1am9_A, 5gnj_I, 7d8t_A, 4h10_A, 5nj8_D, 8osl_P
Binding Motifs: M0177 / MA1362.1 rwkwdgbCACGTGmk
MA1362.2 kwdgbCACGTGm
Publications: Fernández-Calvo P, Chini A, Fernández-Barbero G, Chico J.M, Gimenez-Ibanez S, Geerinck J, Eeckhout D, Schweizer F, Godoy M, Franco-Zorrilla J.M, Pauwels L, Witters E, Puga M.I, Paz-Ares J, Goossens A, Reymond P, De Jaeger G, Solano R. The Arabidopsis bHLH transcription factors MYC3 and MYC4 are targets of JAZ repressors and act additively with MYC2 in the activation of jasmonate responses. The Plant cell 23:701-15 (2011). [Pubmed]
Related annotations: PaperBLAST

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