Transcription Factor

						

			
Accessions: 1exi_A (3D-footprint 20231221), 1exj_A (3D-footprint 20231221)

			
Names: BMRR_BACSU, MULTIDRUG-EFFLUX TRANSPORTER REGULATOR
Organisms: Bacillus subtilis, strain 168
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: P39075
Length: 275
Pfam Domains:      4-71 MerR HTH family regulatory protein
     5-43 MerR family regulatory protein
  122-274 GyrI-like small molecule binding domain
Sequence: 
(in bold interface residues)		   1 ESYYSIGEVSKLANVSIKALRYYDKIDLFKPAYVDPDTSYRYYTDSQLIHLDLIKSLKYI   60
  61 GTPLEEMKKAQDLEMEELFAFYTEQERQIREKLDFLSALEQTISLVKKRMKRQMEYPALG  120
 121 EVFVLDEEEIRIIQTEAEGIGPENVLNASYSKLKKFIESADGFTNNSYGATFSFQPYTSI  180
 181 DEMTYRHIFTPVLTNKQISSITPDMEITTIPKGRYACIAYNFSPEHYFLNLQKLIKYIAD  240
 241 RQLTVVSDVYELIIPIHYSPKKQEEYRVEMKIRIA
Interface Residues: 18, 21, 22, 25, 38, 40, 41
3D-footprint Homologues: 1r8e_A, 5d8c_A, 6xl5_H, 2vz4_A, 6jgx_B, 7ckq_G, 2zhg_A, 6ldi_G, 1r8d_B, 7tea_B, 4r24_B, 6xh7_H
Binding Motifs: 1exi_A CCCT
1exj_A cCcT
Binding Sites: 1exi_M / 1exj_M
			
Publications: Heldwein E.E, Brennan R.G. Crystal structure of the transcription activator BmrR bound to DNA and a drug. Nature 409:378-82 (2001). [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
Disclaimer and license


These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.