Transcription Factor
| Accessions: | A1JVI8 (JASPAR 2024) |
| Names: | A1JVI8_MOUSE |
| Organisms: | Mus musculus |
| Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Uniprot: | A1JVI8 |
| Length: | 674 |
| Pfam Domains: | 19-72 Homeobox domain 113-168 Homeobox domain |
| Sequence: (in bold interface residues) | 1 MAEAGSPVGGSGVARESRRRRKTVWQAWQEQALLSTFKKKRYLSFKERKELAKRMGVSDC 60 61 RIRVWFQNRRNRSGEEGHASKRSIRGSRRLASPQLQEELGSRPQGRGMRSSGRRPRTRLT 120 121 SLQLRILGQAFERNPRPGFATREELARDTGLPEDTIHIWFQNRRARRRHRRGRPTAQDQD 180 181 LLASQGSDGAPAGPEGREREGAQENLLPQEEAGSTGMDTSSPSDLPSFCGESQPFQVAQP 240 241 RGAGQQEAPTRAGNAGSLEPLLDQLLDEVQVEEPAPAPLNLDGDPGGRVHEGSQESFWPQ 300 301 EEAGSTGMDTSSPSDSNSFCRESQPSQVAQPCGAGQEDARTQADSTGPLELLLLDQLLDE 360 361 VQKEEHVPVPLDWGRNPGSREHEGSQDSLLPLEEAVNSGMDTSIPSIWPTFCRESQPPQV 420 421 AQPSGPGQAQAPTQGGNTDPLELFLYQLLDEVQVEEHAPAPLNWDVDPGGRVHEGSWESF 480 481 WPQEEAGSTGLDTSSPSDSNSFFRESKPSQVAQRRGAGQEDARTQADSTGPLELLLFDQL 540 541 LDEVQKEEHVPAPLDWGRNPGSMEHEGSQDSLLPLEEAANSGRDTSIPSIWPAFCRKSQP 600 601 PQVAQPSGPGQAQAPIQGGNTDPLELFLDQLLTEVQLEEQGPAPVNVEETWEQMDTTPDL 660 661 PLTSEEYQTLLDML |
| Interface Residues: | 19, 20, 21, 22, 60, 63, 64, 67, 68, 71, 72, 106, 113, 114, 115, 116, 118, 154, 155, 157, 158, 161, 162, 165, 166, 167, 168, 169 |
| 3D-footprint Homologues: | 5zfz_A, 1puf_A, 2h1k_B, 1zq3_P, 1nk2_P, 7q3o_C, 6es3_K, 4cyc_A, 2hdd_A, 1au7_A, 5jlw_D, 2r5y_A, 4xrs_G, 2hos_A, 1le8_A, 5flv_I, 1du0_A, 4qtr_D, 3a01_E, 3rkq_B, 1ig7_A, 5zjt_E, 6a8r_A, 3cmy_A, 1fjl_B, 3d1n_M, 6m3d_C, 1jgg_B, 3lnq_A, 2lkx_A, 2ld5_A, 1b72_A, 2d5v_B, 7psx_B, 5hod_A, 1puf_B, 3l1p_A, 2xsd_C, 1e3o_C, 7xrc_C, 8g87_X, 4xrm_B |
| Binding Motifs: | MA0611.1 sCAATCAa MA0611.2 ywGATTbAATCAcwww MA0611.3 wGATTbAATCA |
| Binding Sites: | MA0611.2.1 / MA0611.2.2 MA0611.2.10 / MA0611.2.13 MA0611.2.11 / MA0611.2.15 MA0611.2.12 / MA0611.2.16 MA0611.2.13 / MA0611.2.20 MA0611.2.14 MA0611.2.15 MA0611.2.16 MA0611.2.17 MA0611.2.18 MA0611.2.19 MA0611.2.2 / MA0611.2.4 MA0611.2.20 MA0611.2.3 / MA0611.2.5 MA0611.2.4 / MA0611.2.6 MA0611.2.5 / MA0611.2.7 MA0611.2.6 / MA0611.2.8 MA0611.2.10 / MA0611.2.7 MA0611.2.11 / MA0611.2.8 MA0611.2.12 / MA0611.2.9 MA0611.2.1 MA0611.2.14 MA0611.2.17 MA0611.2.18 MA0611.2.19 MA0611.2.3 MA0611.2.9 MA0611.3.1 / MA0611.3.14 / MA0611.3.15 / MA0611.3.19 / MA0611.3.3 / MA0611.3.5 MA0611.3.10 MA0611.3.11 MA0611.3.12 MA0611.3.13 / MA0611.3.16 / MA0611.3.18 / MA0611.3.4 / MA0611.3.6 MA0611.3.17 MA0611.3.2 MA0611.3.20 MA0611.3.7 MA0611.3.8 MA0611.3.9 |
| Publications: | Young JM, Whiddon JL, Yao Z, Kasinathan B, Snider L, Geng LN, Balog J, Tawil R, van der Maarel SM, Tapscott SJ. DUX4 binding to retroelements creates promoters that are active in FSHD muscle and testis. PLoS Genet : (2013). [Pubmed] |
| Related annotations: | PaperBLAST |
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.