Transcription Factor

						

			
Accessions: Q15583 (JASPAR 2024)

			
Names: 5'-TG-3'-interacting factor 1, Homeobox protein TGIF1, TGIF1_HUMAN
Organisms: Homo sapiens
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Uniprot: Q15583
Length: 401
Pfam Domains:   165-221 Homeobox domain
  182-221 Homeobox KN domain
Sequence: 
(in bold interface residues)		   1 MVLAQSRVSAGVGSPHCSGSGGGGSDSFPWPASHPGNPQCSFSTAFLASPRLSRGTLAYL   60
  61 PPAPWSSLATPSALLGSSCAPPPPPARCPQPRALSPELGTKAGPRRPHRWELPRSPSQGA  120
 121 QGPAPRRRLLETMKGIVAASGSETEDEDSMDIPLDLSSSAGSGKRRRRGNLPKESVQILR  180
 181 DWLYEHRYNAYPSEQEKALLSQQTHLSTLQVCNWFINARRRLLPDMLRKDGKDPNQFTIS  240
 241 RRGAKISETSSVESVMGIKNFMPALEETPFHSCTAGPNPTLGRPLSPKPSSPGSVLARPS  300
 301 VICHTTVTALKDVPFSLCQSVGVGQNTDIQQIAAKNFTDTSLMYPEDTCKSGPSTNTQSG  360
 361 LFNTPPPTPPDLNQDFSGFQLLVDVALKRAAEMELQAKLTA
Interface Residues: 164, 165, 166, 167, 168, 169, 170, 212, 213, 216, 217, 218, 220, 221
3D-footprint Homologues: 4j19_B, 3cmy_A, 6fqp_B, 1zq3_P, 2lkx_A, 1mnm_C, 1puf_B, 1au7_A, 1k61_B, 1le8_A, 6fqq_E, 4xrm_B, 1du0_A, 7psx_B, 1le8_B, 5zjt_E, 2d5v_B, 1fjl_B, 2hdd_A, 2hos_A
Binding Motifs: MA0796.1 TGACAGCTGTCA
			
Publications: Bertolino E., Reimund B., Wildt-Perinic D., Clerc R. G. A novel homeobox protein which recognizes a TGT core and functionally interferes with a retinoid-responsive motif. J. Biol. Chem. 270:31178-31188 (1995). [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
Disclaimer and license


These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.