Transcription Factor
Accessions: | P97474 (JASPAR 2024) |
Names: | ALL1-responsive protein ARP1, BRX1 homeoprotein, Homeobox protein PITX2, Orthodenticle-like homeobox 2, Paired-like homeodomain transcription factor 2, Paired-like homeodomain transcription factor Munc 30, Pituitary homeobox 2, PITX2_MOUSE, Solurshin |
Organisms: | Mus musculus |
Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
Length: | 317 |
Pfam Domains: | 86-142 Homeobox domain 274-293 OAR domain |
Sequence: (in bold interface residues) | 1 METNCRKLVSACVQLGVQPAAVECLFSKDSEIKKVEFTDSPKSRKESASSKLFPRQHPGA 60 61 NEKDKGQQGKNEDVGAEDPSKKKRQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAV 120 121 WTNLTEARVRVWFKNRRAKWRKRERNQQAELCKNGFGPQFNGLMQPYDDMYPGYSYNNWA 180 181 AKGLTSASLSTKSFPFFNSMNVNPLSSQSMFSPPNSISSMSMSSSMVPSAVTGVPGSSLN 240 241 SLNNLNNLSSPSLNSAVPTPACPYAPPTPPYVYRDTCNSSLASLRLKAKQHSSFGYASVQ 300 301 NPASNLSACQYAVDRPV |
Interface Residues: | 28, 29, 30, 33, 34, 86, 87, 88, 89, 91, 127, 128, 130, 131, 134, 135, 137, 138, 139, 140, 141, 142 |
3D-footprint Homologues: | 3d1n_M, 2h1k_B, 1puf_A, 6a8r_A, 3cmy_A, 1fjl_B, 5zfz_A, 1ig7_A, 3lnq_A, 2lkx_A, 1jgg_B, 1nk2_P, 1zq3_P, 4j19_B, 1mnm_C, 7q3o_C, 6es3_K, 2ld5_A, 7psx_B, 5hod_A, 2hdd_A, 5jlw_D, 3rkq_B, 2r5y_A, 1puf_B, 4xrs_G, 2hos_A, 4cyc_A, 3a01_E, 6m3d_C, 1b72_A, 5flv_I, 3l1p_A, 5zjt_E, 1e3o_C, 1le8_A, 1le8_B, 1du0_A, 4qtr_D, 1k61_B, 8g87_X, 1o4x_A, 3bm3_A |
Binding Motifs: | PH0138.1 kkwrrGGATTAAthrwy |
Publications: | Berger M.F, Badis G, Gehrke A.R, Talukder S, Philippakis A.A, Peña-Castillo L, Alleyne T.M, Mnaimneh S, Botvinnik O.B, Chan E.T, Khalid F, Zhang W, Newburger D, Jaeger S.A, Morris Q.D, Bulyk M.L, Hughes T.R. Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences. Cell 133:1266-76 (2008). [Pubmed] |
Related annotations: | PaperBLAST |
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.