Transcription Factor

Accessions: T016905_1.02 (CISBP 1.02)
Names: HLH54F, T016905_1.02;
Organisms: Drosophila melanogaster
Libraries: CISBP 1.02 1
1 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed]
Notes: experiment type:B1H, family:bHLH
Length: 242
Pfam Domains: 32-83 Helix-loop-helix DNA-binding domain
Sequence:
(in bold interface residues)
1 MPRKKRSSSPTEFFDDDFDEDASSQSSQPPVQRNAANARERMRMRVLSSAYGRLKTKLPN 60
61 IPPDTKLSKLDTLRLATLYIKQLITAVETGSHSQNHPHNHNQHHSLNHSHSSTTSSEGLD 120
121 TSHMADSSGGGNYNFHNNGHGMSWPFEFHQSSRSLAFAPSSSTTSSARMDWQTLHTQSYP 180
181 KTTRGETHVSADLSYHQLPESHSHWYPAEVHQMEPAASCSYDSGMGQHQRGIAIATSHAH 240
241 GI
Interface Residues: 33, 36, 37, 39, 40, 41, 43, 44
3D-footprint Homologues: 2ypa_A, 6od3_F, 2ypa_B, 2ql2_A, 2ql2_D
Binding Motifs: M5018_1.02 brrCAGGTGkk
Related annotations: PaperBLAST

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