Transcription Factor

Accessions: 4oor_E (3D-footprint 20231221), 4ov7_E (3D-footprint 20231221)
Names: Ancestral Steroid Receptor 2 DNA binding domain, Ancestral Steroid Receptor 2 DBD helix mutant
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Length: 72
Pfam Domains: 4-71 Zinc finger, C4 type (two domains)
Sequence:
(in bold interface residues)
1 PQKVCLICGDEASGCHYGVLTCGSCKVFFKRAVEGQHNYLCAGRNDCIIDKIRRKNCPAC 60
61 RLRKCLQAGMTL
Interface Residues: 13, 14, 16, 17, 23, 24, 26, 27, 30, 31, 55
3D-footprint Homologues: 6fbq_A, 6l6q_B, 7wnh_D, 1lo1_A, 3g9m_B, 1a6y_A, 4oln_B, 2ff0_A, 1dsz_A, 4umm_E, 3cbb_A, 8cef_H, 4iqr_B, 2han_A, 1hcq_E, 8hbm_B, 5krb_G, 2han_B, 1kb2_B, 2a66_A, 2nll_B, 1lat_A, 7xv6_B, 4hn5_B, 5emc_A, 7prw_B, 5cbx_B, 3g6t_A, 1r4i_A, 5cbz_E, 4tnt_B, 5e69_A
Binding Motifs: 4oor_EF GnaCAnnnTGtnnA
4ov7_EF TnnnCAnnnTGTnC
Publications: McKeown A.N, Bridgham J.T, Anderson D.W, Murphy M.N, Ortlund E.A, Thornton J.W. Evolution of DNA specificity in a transcription factor family produced a new gene regulatory module. Cell 159:58-68 (2014). [Pubmed]
Related annotations: PaperBLAST

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