Transcription Factor
| Accessions: | P10627 (JASPAR 2024) |
| Names: | TWIST_DROME |
| Organisms: | Drosophila melanogaster |
| Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Uniprot: | P10627 |
| Length: | 490 |
| Pfam Domains: | 363-413 Helix-loop-helix DNA-binding domain |
| Sequence: (in bold interface residues) | 1 MMSARSVSPKVLLDISYKPTLPNIMELQNNVIKLIQVEQQAYMQSGYQLQHQQQHLHSHQ 60 61 HHQQHHQQQHAQYAPLPSEYAAYGITELEDTDYNIPSNEVLSTSSNQSAQSTSLELNNNN 120 121 TSSNTNSSGNNPSGFDGQASSGSSWNEHGKRARSSGDYDCQTGGSLVMQPEHKKLIHQQQ 180 181 QQQQQHQQQIYVDYLPTTVDEVASAQSCPGVQSTCTSPQSHFDFPDEELPEHKAQVFLPL 240 241 YNNQQQQSQQLQQQQPHQQSHAQMHFQNAYRQSFEGYEPANSLNGSAYSSSDRDDMEYAR 300 301 HNALSSVSDLNGGVMSPACLADDGSAGSLLDGSDAGGKAFRKPRRRLKRKPSKTEETDEF 360 361 SNQRVMANVRERQRTQSLNDAFKSLQQIIPTLPSDKLSKIQTLKLATRYIDFLCRMLSSS 420 421 DISLLKALEAQGSPSAYGSASSLLSAAANGAEADLKCLRKANGAPIIPPEKLSYLFGVWR 480 481 MEGDAQHQKA |
| Interface Residues: | 364, 367, 368, 370, 371, 372, 374, 375 |
| 3D-footprint Homologues: | 2ypa_A, 7z5k_B, 6od3_F, 5eyo_A, 2ql2_D, 2ql2_A, 2ypa_B, 5gnj_I |
| Binding Motifs: | MA0249.1 ycgCAyrTGTtg MA0249.2 ryACACATGta MA0249.3 ACACATG |
| Binding Sites: | MA0249.1.1 MA0249.1.10 MA0249.1.11 MA0249.1.12 MA0249.1.13 MA0249.1.14 MA0249.1.15 MA0249.1.2 MA0249.1.3 MA0249.1.4 MA0249.1.5 MA0249.1.6 MA0249.1.7 MA0249.1.8 MA0249.1.9 MA0249.2.1 MA0249.2.10 / MA0249.2.8 MA0249.2.11 / MA0249.2.9 MA0249.2.10 / MA0249.2.12 MA0249.2.13 MA0249.2.12 / MA0249.2.14 MA0249.2.13 / MA0249.2.15 MA0249.2.14 / MA0249.2.16 MA0249.2.15 / MA0249.2.17 MA0249.2.16 / MA0249.2.18 MA0249.2.17 / MA0249.2.19 MA0249.2.2 MA0249.2.18 / MA0249.2.19 / MA0249.2.20 MA0249.2.2 / MA0249.2.3 MA0249.2.3 / MA0249.2.4 MA0249.2.4 / MA0249.2.5 MA0249.2.5 / MA0249.2.6 / MA0249.2.7 / MA0249.2.8 MA0249.2.9 MA0249.2.1 MA0249.2.11 MA0249.2.20 MA0249.3.1 MA0249.3.10 / MA0249.3.13 / MA0249.3.14 / MA0249.3.15 / MA0249.3.16 / MA0249.3.17 / MA0249.3.18 / MA0249.3.19 / MA0249.3.20 / MA0249.3.4 / MA0249.3.5 / MA0249.3.6 / MA0249.3.7 / MA0249.3.9 MA0249.3.11 MA0249.3.12 MA0249.3.2 / MA0249.3.8 MA0249.3.3 |
| Publications: | Bergman C.M, Carlson J.W, Celniker S.E. Drosophila DNase I footprint database: a systematic genome annotation of transcription factor binding sites in the fruitfly, Drosophila melanogaster. Bioinformatics (Oxford, England) 21:1747-9 (2005). [Pubmed] Nitta KR, Jolma A, Yin Y, Morgunova E, Kivioja T, Akhtar J, Hens K, Toivonen J, Deplancke B, Furlong EE, Taipale J. Conservation of transcription factor binding specificities across 600 million years of bilateria evolution. Elife : (2015). [Pubmed] |
| Related annotations: | PaperBLAST |
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.