Transcription Factor
Accessions: | P31360 (JASPAR 2024) |
Names: | Brain-2, Brain-specific homeobox/POU domain protein 2, Brn-2, Nervous system-specific octamer-binding transcription factor N-Oct-3, Oct-7, Octamer-binding protein 7, Octamer-binding transcription factor 7, OTF-7, PO3F2_MOUSE, POU domain, class 3, transcription factor 2 |
Organisms: | Mus musculus |
Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
Length: | 445 |
Pfam Domains: | 265-338 Pou domain - N-terminal to homeobox domain 357-413 Homeobox domain |
Sequence: (in bold interface residues) | 1 MATAASNHYSLLTSSASIVHAEPPGGMQQGAGGYREAQSLVQGDYGALQSNGHPLSHAHQ 60 61 WITALSHGGGGGGGGGGGGGGGGGGGGGDGSPWSTSPLGQPDIKPSVVVQQGGRGDELHG 120 121 PGALQQQHQQQQQQQQQQQQQQQQQQQQQQQRPPHLVHHAANHHPGPGAWRSAAAAAHLP 180 181 PSMGASNGGLLYSQPSFTVNGMLGAGGQPAGLHHHGLRDAHDEPHHADHHPHPHSHPHQQ 240 241 PPPPPPPQGPPGHPGAHHDPHSDEDTPTSDDLEQFAKQFKQRRIKLGFTQADVGLALGTL 300 301 YGNVFSQTTICRFEALQLSFKNMCKLKPLLNKWLEEADSSSGSPTSIDKIAAQGRKRKKR 360 361 TSIEVSVKGALESHFLKCPKPSAQEITSLADSLQLEKEVVRVWFCNRRQKEKRMTPPGGT 420 421 LPGAEDVYGGSRDTPPHHGVQTPVQ |
Interface Residues: | 290, 306, 307, 308, 309, 311, 312, 318, 322, 355, 357, 358, 359, 360, 398, 399, 401, 402, 405, 406, 409, 410, 413 |
3D-footprint Homologues: | 7u0g_M, 3l1p_A, 3d1n_M, 2xsd_C, 1e3o_C, 7xrc_C, 1au7_A, 1o4x_A, 8g87_X, 3lnq_A, 5zfz_A, 1fjl_B, 3cmy_A, 2h1k_B, 5zjt_E, 1puf_A, 1ig7_A, 6a8r_A, 1jgg_B, 1nk2_P, 1zq3_P, 2lkx_A, 2ld5_A, 1puf_B, 4xrs_G, 3a01_E, 1b72_A, 3rkq_B, 2r5y_A, 5hod_A, 5jlw_D, 1le8_A, 7q3o_C, 4cyc_A, 6es3_K, 1k61_B, 7psx_B, 5flv_I, 2hdd_A, 1mnm_C, 1du0_A |
Binding Motifs: | PH0147.1 swtAaTTAATTArkkyr |
Publications: | Berger M.F, Badis G, Gehrke A.R, Talukder S, Philippakis A.A, Peña-Castillo L, Alleyne T.M, Mnaimneh S, Botvinnik O.B, Chan E.T, Khalid F, Zhang W, Newburger D, Jaeger S.A, Morris Q.D, Bulyk M.L, Hughes T.R. Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences. Cell 133:1266-76 (2008). [Pubmed] |
Related annotations: | PaperBLAST |
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.