Transcription Factor
| Accessions: | usp (DrosophilaTF 1.1), P20153 (JASPAR 2024) |
| Names: | Chorion factor 1, Nuclear receptor subfamily 2 group B member 4, Protein ultraspiracle, USP_DROME, XR2C |
| Organisms: | Drosophila melanogaster |
| Libraries: | DrosophilaTF 1.1 1, JASPAR 2024 2 1 Down T.A, Bergman C.M, Su J, Hubbard T.J. Large-scale discovery of promoter motifs in Drosophila melanogaster. PLoS computational biology 3:e7 (2007). [Pubmed] 2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Length: | 508 |
| Pfam Domains: | 103-171 Zinc finger, C4 type (two domains) 278-480 Ligand-binding domain of nuclear hormone receptor |
| Sequence: (in bold interface residues) | 1 MDNCDQDASFRLSHIKEEVKPDISQLNDSNNSSFSPKAESPVPFMQAMSMVHVLPGSNSA 60 61 SSNNNSAGDAQMAQAPNSAGGSAAAAVQQQYPPNHPLSGSKHLCSICGDRASGKHYGVYS 120 121 CEGCKGFFKRTVRKDLTYACRENRNCIIDKRQRNRCQYCRYQKCLTCGMKREAVQEERQR 180 181 GARNAAGRLSASGGGSSGPGSVGGSSSQGGGGGGGVSGGMGSGNGSDDFMTNSVSRDFSI 240 241 ERIIEAEQRAETQCGDRALTFLRVGPYSTVQPDYKGAVSALCQVVNKQLFQMVEYARMMP 300 301 HFAQVPLDDQVILLKAAWIELLIANVAWCSIVSLDDGGAGGGGGGLGHDGSFERRSPGLQ 360 361 PQQLFLNQSFSYHRNSAIKAGVSAIFDRILSELSVKMKRLNLDRRELSCLKAIILYNPDI 420 421 RGIKSRAEIEMCREKVYACLDEHCRLEHPGDDGRFAQLLLRLPALRSISLKCQDHLFLFR 480 481 ITSDRPLEELFLEQLEAPPPPGLAMKLE |
| Interface Residues: | 112, 113, 115, 116, 122, 123, 125, 126, 129, 130, 154, 176, 178, 180, 183, 188 |
| 3D-footprint Homologues: | 6fbq_A, 6l6q_B, 7wnh_D, 1lo1_A, 3g9m_B, 1a6y_A, 4oln_B, 2nll_B, 1lat_A, 7xv6_B, 2ff0_A, 1dsz_A, 4umm_E, 3cbb_A, 8cef_H, 4iqr_B, 2han_A, 1hcq_E, 8hbm_B, 5krb_G, 2han_B, 1kb2_B, 2a66_A, 4tnt_B, 5e69_A, 4hn5_B, 5emc_A, 7prw_B, 5cbx_B, 3g6t_A, 1r4i_A, 5cbz_E |
| Binding Motifs: | usp GGGGTCACg MA0534.1 vrGkTyRwTGmmyyy MA0016.1 GGGGTCAcgs MA0016.2 GGGGTCAcg |
| Binding Sites: | usp_1 usp_10 usp_11 usp_12 usp_13 usp_14 usp_15 usp_16 usp_17 usp_18 usp_19 usp_2 usp_20 usp_21 usp_22 usp_23 usp_24 usp_25 usp_26 usp_27 usp_28 usp_29 usp_3 usp_30 usp_31 usp_32 usp_33 usp_34 usp_35 usp_36 usp_37 usp_38 usp_4 usp_5 usp_6 usp_7 usp_8 usp_9 MA0016.1.1 MA0016.1.10 MA0016.1.11 MA0016.1.12 MA0016.1.13 MA0016.1.14 MA0016.1.15 MA0016.1.16 MA0016.1.17 MA0016.1.18 MA0016.1.19 MA0016.1.2 MA0016.1.20 MA0016.1.3 MA0016.1.4 MA0016.1.5 MA0016.1.6 MA0016.1.7 MA0016.1.8 MA0016.1.9 MA0534.1.1 MA0534.1.10 MA0534.1.11 MA0534.1.12 MA0534.1.13 MA0534.1.14 MA0534.1.15 MA0534.1.16 MA0534.1.17 MA0534.1.18 MA0534.1.19 MA0534.1.2 MA0534.1.20 MA0534.1.3 MA0534.1.4 MA0534.1.5 MA0534.1.6 MA0534.1.7 MA0534.1.8 MA0534.1.9 MA0016.2.1 / MA0016.2.10 / MA0016.2.11 / MA0016.2.13 / MA0016.2.14 / MA0016.2.5 / MA0016.2.6 / MA0016.2.7 MA0016.2.12 MA0016.2.15 MA0016.2.16 MA0016.2.17 / MA0016.2.18 MA0016.2.19 MA0016.2.2 MA0016.2.20 MA0016.2.3 MA0016.2.4 MA0016.2.8 MA0016.2.9 |
| Publications: | Christianson A. M. K., King D. L., Hatzivassiliou E., Casas J. E., Hallenbeck P. L., Nikodem V. M., Mitsialis S. A., Kafatos F. C. DNA binding and heteromerization of the Drosophila transcription factor chorion factor 1/ultraspiracle. Proc. Natl. Acad. Sci. USA 89:11503-11507 (1992). [Pubmed] Antoniewski C, Mugat B, Delbac F, Lepesant J.A. Direct repeats bind the EcR/USP receptor and mediate ecdysteroid responses in Drosophila melanogaster. Molecular and cellular biology 16:2977-86 (1996). [Pubmed] |
| Related annotations: | PaperBLAST |
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