Transcription Factor
| Accessions: | T061566_1.02 (CISBP 1.02), Q12139 (JASPAR 2024) |
| Names: | T061566_1.02;, YPR022C, YP022_YEAST |
| Organisms: | Saccharomyces cerevisiae |
| Libraries: | CISBP 1.02 1, JASPAR 2024 2 1 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed] 2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Notes: | experiment type:PBM, family:C2H2 ZF |
| Length: | 1134 |
| Pfam Domains: | 31-55 C2H2-type zinc finger 31-55 Zinc finger, C2H2 type 61-91 C2H2-type zinc finger 506-824 Fungal specific transcription factor domain |
| Sequence: (in bold interface residues) | 1 MHGKELAGRLRKRENDNDLSPNSSSSPAERFRCPHPECNKTFSRQEHLSRHKLNHWPKEI 60 61 YVCSYVLPTTNAPCNKTFVRKDLLIRHEKRHSKVKNRLSRPSKDQISSSNKDFSKNAPYN 120 121 PSEVPLSTQSGTSTINLIKNSVNPPPSITQESKFRPFLQQAQQPQQVQQSQQPQQIQQLQ 180 181 QLQFPQQLRAPLQQPMLQQQMHPQQASPTFPSYDPRIRNNGQNGNQFFNLIFDNRTGVNG 240 241 FEVDAANNNGNGNDQNMNINPAVQQQRYQDRNFASSSYQQPLQPLTQDQQQEQYFQQQKL 300 301 AQQQQQQQQQQQQQQQLPPQNPFGDPLTSSSSGANLSVMQDLFSTNFLNSDPLQSFMQEL 360 361 SEAPQVSIEDTFSDKNTIPPNEKPVQQDEGFQNPPVMFELPQDNIKIPKAQPKFNDNPST 420 421 SVKDNLSSQKLNINELKRRSSKDSGVGNNSSLNYKEQLRHSMKSVPSFFHPDPLTKYKIS 480 481 KEKCQEMFSFVPELRYVSIESIHKSLKSFWLNFHPQYGLLHKPSFHVDKQPAILNLALIM 540 541 TGASFLGSEYREQISDPICGPLRWIIFSHADFQPPSKTYIIQSLLLVEGYEKTSTNRYLH 600 601 ERSFLHHGTTIQLLRRTPSLGGHPLMVKTGKTSGENSIQDPQEVYKRWIDFEMLKRIAFY 660 661 AFYMDTTHAVVFGYWNLFINSNQIQLTLPCPDQVWESYDLSYETLMEHGYGSTKRDENNT 720 721 FLSALMQLMKNVIQILRNNNIRRNKVNNGGIESTPTDLESTTDWNIQSLFGKKILLAGII 780 781 SILFQCQEEVNGDYFITNFRGGITDHLGLSWKDILSFAMNYWLHEVQKSCTDPKACRIST 840 841 PSEETLTNRKIDEDNGDGLCDDDLDLLSSDNPSNCKIPVIHISQIVLRILHHDYYIYAGA 900 901 PWRMNVPIGRDEYDMISRRILQFAKDPYNGGVAVVYAFQFLFEMFIIKENNVPTVVKSYN 960 961 INSDPVITRPYAIALTSLLIWSCNFALHGCEVSIWDNTEASKDECFQPDDSNGGNI LGN 1020 1021 TDNNGSTIANNNLKEKNNYIPIESFEVYLLRMYRNLYVDSSLDVVSFQNDVWAKASLLQH 1080 1081 ISNTHFLCGMMQFMRDIFNKSYWDLGREFGKLFDNCLERSLGKTSPTCHNMFDV |
| Interface Residues: | 5, 8, 42, 43, 44, 45, 46, 47, 49, 50, 52, 53, 54, 56, 65, 79, 80, 81, 82, 83, 84, 86, 87, 90, 102, 104, 105, 106, 107, 108, 109, 110, 111, 129, 132 |
| 3D-footprint Homologues: | 5v3j_F, 7w1m_H, 7n5w_A, 6ml4_A, 5und_A, 1llm_D, 5k5i_A, 8gn3_A, 6u9q_A, 1mey_C, 6blw_A, 5k5l_F, 2gli_A, 5yel_A, 4x9j_A, 6e94_A, 5kl3_A, 2i13_A, 1f2i_J, 8ssq_A, 7eyi_G, 5ei9_F, 8h9h_G, 7ysf_A, 6wmi_A, 1tf3_A, 1tf6_A, 2jpa_A, 1ubd_C, 2wbs_A, 7txc_E, 5yj3_D, 6a57_A |
| Binding Motifs: | M0543_1.02 arcGTGGGg MA0436.1 cCCCACs MA0436.2 cCCCAC |
| Publications: | Badis G, Chan E.T, van Bakel H, Pena-Castillo L, Tillo D, Tsui K, Carlson C.D, Gossett A.J, Hasinoff M.J, Warren C.L, Gebbia M, Talukder S, Yang A, Mnaimneh S, Terterov D, Coburn D, Li Yeo A, Yeo Z.X, Clarke N.D, Lieb J.D, Ansari A.Z, Nislow C, Hughes T.R. A library of yeast transcription factor motifs reveals a widespread function for Rsc3 in targeting nucleosome exclusion at promoters. Molecular cell 32:878-87 (2008). [Pubmed] |
| Related annotations: | PaperBLAST |
Disclaimer and license
These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.