Transcription Factor

Accessions: MYB3R5 (JASPAR 2024), T22271 (AthalianaCistrome v4_May2016), Q6R032 (JASPAR 2024)
Names: MB3R5_ARATH, Myb-related protein 3R-5, Transcription factor MYB3R-5, AT5G02320, MYB3R5, T22271;
Organisms: Arabidopsis thaliana
Libraries: JASPAR 2024 1, AthalianaCistrome v4_May2016 2
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
2 O'Malley RC, Huang SS, Song L, Lewsey MG, Bartlett A, Nery JR, Galli M, Gallavotti A, Ecker JR. Cistrome and Epicistrome Features Shape the Regulatory DNA Landscape. Cell 165:1280-92 (2016). [Pubmed]
Notes: ecotype:Col-0, experiment type: DAP-seq, family:MYB
Length: 548
Pfam Domains: 75-121 Myb-like DNA-binding domain
78-137 Myb-like DNA-binding domain
127-173 Myb-like DNA-binding domain
130-190 Myb-like DNA-binding domain
179-222 Myb-like DNA-binding domain
182-228 Myb-like DNA-binding domain
Sequence:
(in bold interface residues)
1 MSSSSNPPVCSPEKEERSEMKIEIQCMENKQPLAASCSSASEGSGCFFLKSPEIATPATV 60
61 SSFPRRTSGPMRRAKGGWTPEEDETLRRAVEKYKGKRWKKIAEFFPERTEVQCLHRWQKV 120
121 LNPELVKGPWTQEEDDKIVELVKKYGPAKWSVIAKSLPGRIGKQCRERWHNHLNPGIRKD 180
181 AWTVEEESALMNSHRMYGNKWAEIAKVLPGRTDNAIKNHWNSSLKKKLEFYLATGNLPPP 240
241 ASKFIVLKDIADGDRDSKQSSATKPFKDSDSLTQTSSGNTDSNEVGRDHFDSSSALLEEV 300
301 AASRRIGVNEYACSPVEYKPQLPNLEPISEEVRINSKAYFERSIQRKVENGFGTPKHGNL 360
361 YYKSPLDYYFPSEADLQHMYGYECGCSPGAASPVSLMTTPCNKDSGLTATRSPESFLREA 420
421 ARTFPNTPSIFRKRRKVVLAAKTDAVVVVNGVVKEVDRKEESKDMRKSLLLETTDNCSDD 480
481 EELGLNGNAFNLSPPYRLRAKRTAVIKSRQLEFTSEKEKQPDNEIEFTSAKEKQPDNEIK 540
541 TSEEDKPV
Interface Residues: 61, 62, 65, 66, 75, 110, 111, 114, 115, 118, 119, 127, 161, 162, 163, 164, 166, 167, 170, 171, 172, 178, 179, 198, 213, 214, 215, 217, 218, 221, 222, 223
3D-footprint Homologues: 5eyb_B, 1w0t_A, 7c4r_A, 7xur_A, 3osg_A, 1vfc_A, 2kdz_A, 6kks_A, 3zqc_A, 1mse_C, 6cnb_S, 1ign_A
Binding Motifs: M0535 / MA1172.1 aawwwwTdRCCGTTr
MA1172.2 awwwwTdRCCGTTr
Binding Sites: MA1172.1.1
MA1172.1.10 / MA1172.1.9
MA1172.1.11
MA1172.1.12
MA1172.1.13
MA1172.1.14
MA1172.1.15 / MA1172.1.16
MA1172.1.17
MA1172.1.18
MA1172.1.19
MA1172.1.2
MA1172.1.20
MA1172.1.3
MA1172.1.4
MA1172.1.5
MA1172.1.6
MA1172.1.7
MA1172.1.8
MA1172.2.1
MA1172.2.10 / MA1172.2.9
MA1172.2.11
MA1172.2.12
MA1172.2.13
MA1172.2.14
MA1172.2.15 / MA1172.2.16
MA1172.2.17
MA1172.2.18
MA1172.2.19
MA1172.2.2
MA1172.2.20
MA1172.2.3
MA1172.2.4
MA1172.2.5
MA1172.2.6
MA1172.2.7
MA1172.2.8
Publications: Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed]
Related annotations: PaperBLAST

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.