Transcription Factor

Accessions: 2mf8_A (3D-footprint 20231221)
Names: Myelin transcription factor 1, MYT1_MOUSE, Neural zinc finger factor 2, NZF-2
Organisms: Mus musculus
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: Q8CFC2
Length: 75
Pfam Domains: 2-31 Zinc finger, C2HC type
46-75 Zinc finger, C2HC type
Sequence:
(in bold interface residues)
1 LLTCPTPGCDGSGHITGNYASHRSLSGCPLADKSLRNLMAAHSADLKCPTPGCDGSGHIT 60
61 GNYASHRSLSGCPRA
Interface Residues: 13, 14, 17, 21, 23, 24, 25, 26, 36, 37, 58, 59, 62, 63, 65, 67, 68, 69, 70
3D-footprint Homologues: 6wmi_A, 2mf8_A, 2jx1_A
Binding Motifs: 2mf8_A aAAgTTc
Binding Sites: 2mf8_B
2mf8_C
Publications: Gamsjaeger R, O'Connell M.R, Cubeddu L, Shepherd N.E, Lowry J.A, Kwan A.H, Vandevenne M, Swanton M.K, Matthews J.M, Mackay J.P. A structural analysis of DNA binding by myelin transcription factor 1 double zinc fingers. The Journal of biological chemistry 288:35180-91 (2013). [Pubmed]
Related annotations: PaperBLAST

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