Transcription Factor
Accessions: | ALX3_full (HumanTF 1.0) |
Names: | ALX3, ALX3_HUMAN, Homeobox protein aristaless-like 3, Proline-rich transcription factor ALX3 |
Organisms: | Homo sapiens |
Libraries: | HumanTF 1.0 1 1 Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed] |
Uniprot: | O95076 |
Notes: | Ensembl ID: ENSG00000156150; Full protein sequence; TF family: homeodomain; Clone source: hORFeome |
Length: | 344 |
Pfam Domains: | 154-210 Homeobox domain |
Sequence: (in bold interface residues) | 1 MDPEHCAPFRVGPAPGPYVASGDEPPGPQGTPAAAPHLHPAPPRGPRLTRFPACGPLEPY 60 61 LPEPAKPPAKYLQDLGPGPALNGGHFYEGPAEAEEKTSKAASFPQLPLDCRGGPRDGPSN 120 121 LQGSPGPCLASLHLPLSPGLPDSMELAKNKSKKRRNRTTFSTFQLEELEKVFQKTHYPDV 180 181 YAREQLALRTDLTEARVQVWFQNRRAKWRKRERYGKIQEGRNPFTAAYDISVLPRTDSHP 240 241 QLQNSLWASPGSGSPGGPCLVSPEGIPSPCMSPYSHPHGSVAGFMGVPAPSAAHPGIYSI 300 301 HGFPPTLGGHSFEPSSDGDYKSPSLVSLRVKPKEPPGLLNWTT* |
Interface Residues: | 123, 126, 153, 154, 155, 156, 157, 195, 196, 198, 199, 202, 203, 206, 207, 210 |
3D-footprint Homologues: | 1au7_A, 4j19_B, 3cmy_A, 2h1k_B, 1ig7_A, 1puf_A, 6a8r_A, 3d1n_M, 1puf_B, 5zfz_A, 1fjl_B, 2lkx_A, 1jgg_B, 1zq3_P, 6m3d_C, 3lnq_A, 1nk2_P, 7q3o_C, 6es3_K, 2ld5_A, 1b72_A, 5zjt_E, 7psx_B, 5hod_A, 3rkq_B, 2hdd_A, 5jlw_D, 4cyc_A, 2r5y_A, 4xrs_G, 3l1p_A, 2hos_A, 3a01_E, 5flv_I, 1e3o_C, 1le8_A, 4qtr_D, 1du0_A, 4xrm_B |
Binding Motifs: | ALX3_full_1 yyyAATTArm ALX3_full_2 hTAATywaATTAm |
Publications: | Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed] |
Related annotations: | PaperBLAST |
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.