Transcription Factor

Accessions: Q9XEC3 (JASPAR 2024), T16951 (AthalianaCistrome v4_May2016)
Names: WRK42_ARATH, WRKY DNA-binding protein 42, WRKY transcription factor 42, AT4G04450, T16951;, WRKY42
Organisms: Arabidopsis thaliana
Libraries: JASPAR 2024 1, AthalianaCistrome v4_May2016 2
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
2 O'Malley RC, Huang SS, Song L, Lewsey MG, Bartlett A, Nery JR, Galli M, Gallavotti A, Ecker JR. Cistrome and Epicistrome Features Shape the Regulatory DNA Landscape. Cell 165:1280-92 (2016). [Pubmed]
Notes: ecotype:Col-0, experiment type: ampDAP-seq, experiment type: ampDAP-seq (methyl-cytosines removed by PCR), experiment type: DAP-seq, family:WRKY
Length: 528
Pfam Domains: 292-350 WRKY DNA -binding domain
Sequence:
(in bold interface residues)
1 MFRFPVSLGGGPRENLKPSDEQHQRAVVNEVDFFRSAEKRDRVSREEQNIIADETHRVHV 60
61 KRENSRVDDHDDRSTDHINIGLNLLTANTGSDESMVDDGLSVDMEEKRTKCENAQLREEL 120
121 KKASEDNQRLKQMLSQTTNNFNSLQMQLVAVMRQQEDHHHLATTENNDNVKNRHEVPEMV 180
181 PRQFIDLGPHSDEVSSEERTTVRSGSPPSLLEKSSSRQNGKRVLVREESPETESNGWRNP 240
241 NKVPKHHASSSICGGNGSENASSKVIEQAAAEATMRKARVSVRARSEAPMLSDGCQWRKY 300
301 GQKMAKGNPCPRAYYRCTMAVGCPVRKQVQRCAEDRTILITTYEGNHNHPLPPAAMNMAS 360
361 TTTAAASMLLSGSTMSNQDGLMNPTNLLARTILPCSSSMATISASAPFPTITLDLTESPN 420
421 GNNPTNNPLMQFSQRSGLVELNQSVLPHMMGQALYYNQQSKFSGLHMPSQPLNAGESVSA 480
481 ATAAIASNPNFAAALAAAITSIINGSNNQQNGNNNNSNVTTSNVDNRQ
Interface Residues: 298, 299, 300, 302, 303, 314
3D-footprint Homologues: 6ir8_A, 6j4e_B, 6j4f_F, 6j4g_B, 7z0u_A
Binding Motifs: M0839 / MA1310.1 tttkamhyrkcGTTGACywwk
M0838 wwawmwwrGTCAACgmhddk
MA1310.2 cGTTGACy
Publications: Yu D, Chen C, Chen Z. 2001. Evidence for an important role of WRKY DNA binding proteins in the regulation of NPR1 gene expression. Plant Cell. 13:1527-40. [Pubmed]
Related annotations: PaperBLAST

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