Transcription Factor

						

			
Accessions: P45897 (JASPAR 2024)

			
Names: Dwarfin sma-4, MAD protein homolog 3, SMA4_CAEEL
Organisms: Caenorhabditis elegans
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Uniprot: P45897
Length: 570
Pfam Domains:   169-268 MH1 domain
  347-553 MH2 domain
Sequence: 
(in bold interface residues)		   1 MFHPGMTSQPSTSNQMYYDPLYGAEQIVQCNPMDYHQANILCGMQYFNNSHNRYPLLPQM   60
  61 PPQFTNDHPYDFPNVPTISTLDEASSFNGFLIPSQPSSYNNNNISCVFTPTPCTSSQASS  120
 121 QPPPTPTVNPTPIPPNAGAVLTTAMDSCQQISHVLQCYQQGGEDSDFVRKAIESLVKKLK  180
 181 DKRIELDALITAVTSNGKQPTGCVTIQRSLDGRLQVAGRKGVPHVVYARIWRWPKVSKNE  240
 241 LVKLVQCQTSSDHPDNICINPYHYERVVSNRITSADQSLHVENSPMKSEYLGDAGVIDSC  300
 301 SDWPNTPPDNNFNGGFAPDQPQLVTPIISDIPIDLNQIYVPTPPQLLDNWCSIIYYELDT  360
 361 PIGETFKVSARDHGKVIVDGGMDPHGENEGRLCLGALSNVHRTEASEKARIHIGRGVELT  420
 421 AHADGNISITSNCKIFVRSGYLDYTHGSEYSSKAHRFTPNESSFTVFDIRWAYMQMLRRS  480
 481 RSSNEAVRAQAAAVAGYAPMSVMPAIMPDSGVDRMRRDFCTIAISFVKAWGDVYQRKTIK  540
 541 ETPCWIEVTLHRPLQILDQLLKNSSQFGSS
Interface Residues: 211, 213, 215, 220
3D-footprint Homologues: 6fzs_A, 6h3r_A, 5nm9_A, 5od6_A, 5mey_A
Binding Motifs: MA0925.1 arTGTCTGGrc
MA0925.2 TGTCTGG
			
Publications: Massagué J, Seoane J, Wotton D. Smad transcription factors. Genes Dev 19:2783-810 (2005). [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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